Chromogranin A in pituitary adenomas: immunohistochemical detection and plasma concentrations.
| Title: | Chromogranin A in pituitary adenomas: immunohistochemical detection and plasma concentrations. |
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| Authors: | Jolanta Kunert-Radek, Maciej Radek, Anna Gruszka, Marek Pawlikowski |
| Source: | Folia Histochemica et Cytobiologica, Vol 42, Iss 4, Pp 245-247 (2005) |
| Publisher Information: | Via Medica, 2005. |
| Publication Year: | 2005 |
| Collection: | LCC:Cytology |
| Subject Terms: | Cytology, QH573-671 |
| More Details: | Forty one pituitary adenomas excised surgically were immunostained to reveal pituitary hormones and chromogranin A (CgA). In 23 patients, plasma CgA concentration was determined before surgery by ELISA method. The CgA immunopositivity was found in 70.7% of investigated tumors. It was observed in all tumors of gonadotropinoma type and in the majority of null cell adenomas. Elevated (>18 U/L) plasma CgA concentration was observed in approx. a half of the examined patients, being more frequent in gonadotropinomas and null cell adenomas. It may have some, although limited, diagnostic value in these types of pituitary tumors. |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English |
| ISSN: | 0239-8508 1897-5631 |
| Relation: | http://czasopisma.viamedica.pl/fhc/article/view/4633; https://doaj.org/toc/0239-8508; https://doaj.org/toc/1897-5631 |
| DOI: | 10.5603/4633 |
| Access URL: | https://doaj.org/article/c9b2999932b149ed991f1a12e8371fdf |
| Accession Number: | edsdoj.9b2999932b149ed991f1a12e8371fdf |
| Database: | Directory of Open Access Journals |
| ISSN: | 02398508 18975631 |
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| DOI: | 10.5603/4633 |
| Published in: | Folia Histochemica et Cytobiologica |
| Language: | English |