Assessment of ventricular function after total cavo-pulmonary derivation in adult patients: Interest of global longitudinal strain

Bibliographic Details
Title: Assessment of ventricular function after total cavo-pulmonary derivation in adult patients: Interest of global longitudinal strain
Authors: Kaouther Hakim, Nouha Mekki, Rihab Benothmen, Mokbli Malek, Jarray Abdelkader, Msaad Hela, Habiba Mizouni, Ouarda Fatma
Source: Journal of Cardiovascular and Thoracic Research, Vol 15, Iss 4, Pp 262-268 (2023)
Publisher Information: Tabriz University of Medical Sciences, 2023.
Publication Year: 2023
Collection: LCC:Diseases of the circulatory (Cardiovascular) system
Subject Terms: univentricular heart, fontan operation, echocardiography, magnetic resonance imaging, ventricular function, global longitudinal strain, Diseases of the circulatory (Cardiovascular) system, RC666-701
More Details: Ventricular dysfunction is the most frequent complication in adult patients post-Fontan completion. Through this work, we aim to evaluate ventricular systolic function by conventional echographic parameters and by global longitudinal strain (GLS) to determine the prediction of early ventricular systolic dysfunction. This is a prospective monocentric study enrolling 15 clinically stable adult Fontan patients with preserved ejection fraction (EF). Myocardial deformation study by GLS with speckle tracking technique in addition to a standard Doppler transthoracic echocardiography (TTE) was performed. Cardiac magnetic resonance imaging (CMR) was also performed. A comparison of echocardiographic and CMR parameters was made. In comparison to CMR-derived EF, we found a significant correlation with GLS and TTE-derived EF (P=0.003 and 0.014). We divided our population into two groups based on the cut-off value of 50% of CMR derived EF. Comparison of GLS in both groups showed a significant correlation (P=0.003). A cut-off value of -13.3% showed sensitivity of 67% and specificity of 100%. GLS has a moderate diagnostic value for systolic myocardial dysfunction in the population of adult patients with Fontan circulation.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2008-5117
2008-6830
Relation: https://jcvtr.tbzmed.ac.ir/PDF/jcvtr-15-262.pdf; https://doaj.org/toc/2008-5117; https://doaj.org/toc/2008-6830
DOI: 10.34172/jcvtr.2023.32880
Access URL: https://doaj.org/article/9b1f930ad3524af4b26faa9cb3411cf4
Accession Number: edsdoj.9b1f930ad3524af4b26faa9cb3411cf4
Database: Directory of Open Access Journals
More Details
ISSN:20085117
20086830
DOI:10.34172/jcvtr.2023.32880
Published in:Journal of Cardiovascular and Thoracic Research
Language:English