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Standardized Laboratory Procedures, Quality Control and Quality Assurance Are Key Requirements for Accurate Semen Analysis in the Evaluation of Infertile Male

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Title: Standardized Laboratory Procedures, Quality Control and Quality Assurance Are Key Requirements for Accurate Semen Analysis in the Evaluation of Infertile Male
Authors: Ashok Agarwal, Rakesh Sharma, Sajal Gupta, Renata Finelli, Neel Parekh, Manesh Kumar Panner Selvam, Camila Pinho Pompeu, Sarah Madani, Andrea Belo, Mahsa Darbandi, Neha Singh, Sara Darbandi, Simryn Covarrubias, Raha Sadeghi, Mohamed Arafa, Ahmad Majzoub, Meaghanne Caraballo, Alyssa Giroski, Kourtney McNulty, Damayanthi Durairajanayagam, Ralf Henkel
Source: The World Journal of Men's Health, Vol 40, Iss 1, Pp 52-65 (2022)
Publisher Information: Korean Society for Sexual Medicine and Andrology, 2022.
Publication Year: 2022
Collection: LCC:Medicine
LCC:Diseases of the genitourinary system. Urology
Subject Terms: semen analysis, standardization, quality assurance, quality control, Medicine, Diseases of the genitourinary system. Urology, RC870-923
More Details: Semen analysis is a basic test for evaluating male fertility potential, as it plays an essential role in driving the future management and treatment of infertility in couples. Manual semen analysis includes the evaluation of both macroscopic and microscopic parameters, whereas automated semen analysis is conducted through a computer-aided sperm analysis system and can include additional parameters that are not evaluated by manual analysis. Both quality control (QC) and quality assurance (QA) are important to ensure reproducible results for semen analysis, and represent fundamental checks and balances of all stages (pre-analytical, analytical, and post-analytical) of semen analysis. To ensure accuracy and precision, the laboratory technicians’ performance should be evaluated biannually. This narrative review aims to describe standardized laboratory procedures for an accurate assessment of semen parameters that incorporate both QC and QA practices.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2287-4208
2287-4690
Relation: https://doaj.org/toc/2287-4208; https://doaj.org/toc/2287-4690
DOI: 10.5534/wjmh.210022
Access URL: https://doaj.org/article/997c7adeaff74424b5b1cfc947757698
Accession Number: edsdoj.997c7adeaff74424b5b1cfc947757698
Database: Directory of Open Access Journals
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  Data: Standardized Laboratory Procedures, Quality Control and Quality Assurance Are Key Requirements for Accurate Semen Analysis in the Evaluation of Infertile Male
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  Data: Semen analysis is a basic test for evaluating male fertility potential, as it plays an essential role in driving the future management and treatment of infertility in couples. Manual semen analysis includes the evaluation of both macroscopic and microscopic parameters, whereas automated semen analysis is conducted through a computer-aided sperm analysis system and can include additional parameters that are not evaluated by manual analysis. Both quality control (QC) and quality assurance (QA) are important to ensure reproducible results for semen analysis, and represent fundamental checks and balances of all stages (pre-analytical, analytical, and post-analytical) of semen analysis. To ensure accuracy and precision, the laboratory technicians’ performance should be evaluated biannually. This narrative review aims to describe standardized laboratory procedures for an accurate assessment of semen parameters that incorporate both QC and QA practices.
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