Bibliographic Details
| Title: |
Impact of dexmedetomidine on agitation and inflammatory response during recovery from anesthesia in young children following cochlear implantation surgery |
| Authors: |
Qing Cheng, Chao-Yang Chen, Xiang Li, Li-Jun Wu, Ze-Yu Zhao |
| Source: |
BMC Anesthesiology, Vol 25, Iss 1, Pp 1-8 (2025) |
| Publisher Information: |
BMC, 2025. |
| Publication Year: |
2025 |
| Collection: |
LCC:Anesthesiology |
| Subject Terms: |
Anesthesia recovery, Children, Cochlear implantation, Dexmedetomidine, Inflammation, Psychomotor agitation, Anesthesiology, RD78.3-87.3 |
| More Details: |
Abstract Objective To evaluate the impact of dexmedetomidine (Dex) on agitation and inflammatory response during recovery from anesthesia in young children following cochlear implantation surgery. Methods We randomly divided 80 children who underwent unilateral cochlear implantation into two equal groups. Group D received an intravenous infusion of Dex after induction of anesthesia, while those in group C received an equal volume of saline infusion. The mean arterial pressure (MAP) and heart rate (HR) of children in the two groups were recorded at four different time intervals: before induction of anesthesia (T0); 30 min after intravenous infusion of Dex (T1); upon admission to the post-anesthesia care unit (PACU) (T2); and at the time of being transferred out of the PACU (T3). At T3, we also recorded general information. Results The MAP and HR in group D showed more consistent trends during the anesthesia recovery period when compared to those in group C. Children in group D had a significantly lower crying, requires increased O2 administration, increased vital signs, expression and sleepless score (CRIES score), pediatric anesthesia emergence delirium (PAED) score, and incidence of agitation than in group C (P |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
1471-2253 |
| Relation: |
https://doaj.org/toc/1471-2253 |
| DOI: |
10.1186/s12871-025-02970-x |
| Access URL: |
https://doaj.org/article/a99657e7bff64498987a1ad6a9f9aae7 |
| Accession Number: |
edsdoj.99657e7bff64498987a1ad6a9f9aae7 |
| Database: |
Directory of Open Access Journals |
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