Genome-wide association scan for variants associated with early-onset prostate cancer.

Bibliographic Details
Title: Genome-wide association scan for variants associated with early-onset prostate cancer.
Authors: Ethan M Lange, Anna M Johnson, Yunfei Wang, Kimberly A Zuhlke, Yurong Lu, Jessica V Ribado, Gregory R Keele, Jin Li, Qing Duan, Ge Li, Zhengrong Gao, Yun Li, Jianfeng Xu, William B Isaacs, Siqun Zheng, Kathleen A Cooney
Source: PLoS ONE, Vol 9, Iss 4, p e93436 (2014)
Publisher Information: Public Library of Science (PLoS), 2014.
Publication Year: 2014
Collection: LCC:Medicine
LCC:Science
Subject Terms: Medicine, Science
More Details: Prostate cancer is the most common non-skin cancer and the second leading cause of cancer related mortality for men in the United States. There is strong empirical and epidemiological evidence supporting a stronger role of genetics in early-onset prostate cancer. We performed a genome-wide association scan for early-onset prostate cancer. Novel aspects of this study include the focus on early-onset disease (defined as men with prostate cancer diagnosed before age 56 years) and use of publically available control genotype data from previous genome-wide association studies. We found genome-wide significant (p
Document Type: article
File Description: electronic resource
Language: English
ISSN: 1932-6203
Relation: http://europepmc.org/articles/PMC3989171?pdf=render; https://doaj.org/toc/1932-6203
DOI: 10.1371/journal.pone.0093436
Access URL: https://doaj.org/article/98d573dd13d54d61b2bd7817179e867d
Accession Number: edsdoj.98d573dd13d54d61b2bd7817179e867d
Database: Directory of Open Access Journals
More Details
ISSN:19326203
DOI:10.1371/journal.pone.0093436
Published in:PLoS ONE
Language:English