Academic Journal
The admission level of CRP during cardiogenic shock is a strong independent risk marker of mortality
| Title: | The admission level of CRP during cardiogenic shock is a strong independent risk marker of mortality |
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| Authors: | François Roubille, Miloud Cherbi, Eran Kalmanovich, Quentin Delbaere, Eric Bonnefoy-Cudraz, Etienne Puymirat, Guillaume Schurtz, Edouard Gerbaud, Laurent Bonello, Pascal Lim, Guillaume Leurent, Camille Roubille, Clément Delmas |
| Source: | Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024) |
| Publisher Information: | Nature Portfolio, 2024. |
| Publication Year: | 2024 |
| Collection: | LCC:Medicine LCC:Science |
| Subject Terms: | Cardiogenic shock, Inflammation, CRP, Infection, Epidemiology, Prognosis, Medicine, Science |
| More Details: | Abstract Inflammatory processes are involved not only in coronary artery disease but also in heart failure (HF). Cardiogenic shock (CS) and septic shock are classically distinct although intricate relationships are frequent in daily practice. The impact of admission inflammation in patients with CS is largely unknown. FRENSHOCK is a prospective registry including 772 CS patients from 49 centers. One-month and one-year mortalities were analyzed according to the level of C-reactive protein (CRP) at admission, adjusted on independent predictive factors. Within 406 patients included, 72.7% were male, and the mean age was 67.4 y ± 14.7. Four groups were defined, depending on the quartiles of CRP at admission. Q1 with a CRP 28–69 mg/L, and Q4: CRP was > 69 mg/L. The four groups did not differ regarding main baseline characteristics. However, group Q4 received more often antibiotics in 47.5%, norepinephrine in 66.3%, and needed more frequently respiratory support and renal replacement therapy. Whether at 1 month (Ptrend = 0.01) or 1 year (Ptrend |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English |
| ISSN: | 2045-2322 |
| Relation: | https://doaj.org/toc/2045-2322 |
| DOI: | 10.1038/s41598-024-67556-y |
| Access URL: | https://doaj.org/article/98659e3ea9cb449fbfff6c90ba1ca5be |
| Accession Number: | edsdoj.98659e3ea9cb449fbfff6c90ba1ca5be |
| Database: | Directory of Open Access Journals |
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| ISSN: | 20452322 |
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| DOI: | 10.1038/s41598-024-67556-y |
| Published in: | Scientific Reports |
| Language: | English |