Academic Journal
Retinopathy of prematurity in triplets – Indian twin city ROP study report number 12
| Title: | Retinopathy of prematurity in triplets – Indian twin city ROP study report number 12 |
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| Authors: | Manjushree Bhate, Komal Agarwal, Padmaja Kumari Rani, Akash Belenje, Deepika C Parmeshwarappa, Subhadra Jalali |
| Source: | Indian Journal of Ophthalmology, Vol 72, Iss 12, Pp 1780-1785 (2024) |
| Publisher Information: | Wolters Kluwer Medknow Publications, 2024. |
| Publication Year: | 2024 |
| Collection: | LCC:Ophthalmology |
| Subject Terms: | discordance, retinopathy of prematurity, triplet pregnancies, Ophthalmology, RE1-994 |
| More Details: | Purpose: To evaluate the incidence and severity of retinopathy of prematurity (ROP) amongst surviving triplets. Methods: Records of preterm babies born to mothers with triplet pregnancies were retrieved from our Indian twin city ROP study database between 1 Jan 2000 and 31 Dec 2020 and analyzed. Results: 253 surviving triplet babies born to 108 mothers were evaluated. 48 out of 108 (44%) mothers received treatment for infertility. Data was available and analyzed for 242 babies (484 eyes). Mean gestational age was 31.76 ± 3.74 weeks (26- 38 weeks). The mean birth weight was 1.44 ± 0.37 kg (0.57–2.76 kg). At the first screening, incomplete vascularization was noted in 67% (131 babies;322 eyes) of which ROP was diagnosed in 14% (28 babies; 56 eyes). Among them, only 18 babies (53%) were the smallest birth weight babies in each of the triplet sets. Treatment with laser or bevacizumab was performed in 14 babies (5.8%), one eye of one baby additionally needed vitreoretinal surgical intervention. Good anatomical outcomes in terms of regression of ROP without sequelae were achieved in all babies. Conclusion: The present study reveals low incidence and favorable outcomes of ROP in triplet pregnancies in a large cohort of babies from a middle-income country. Our cohort did not show any difference in the treatment-requiring ROP among the larger or smaller birth weight babies of the same gestational age. In multiple pregnancies, gestational age remains a critical factor for ROP development; however, this does not necessitate modifying screening or treatment criteria in such triplet pregnancies. |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English |
| ISSN: | 0301-4738 1998-3689 |
| Relation: | https://journals.lww.com/10.4103/IJO.IJO_1700_23; https://doaj.org/toc/0301-4738; https://doaj.org/toc/1998-3689 |
| DOI: | 10.4103/IJO.IJO_1700_23 |
| Access URL: | https://doaj.org/article/98184cfab04247498283963cb4b4518d |
| Accession Number: | edsdoj.98184cfab04247498283963cb4b4518d |
| Database: | Directory of Open Access Journals |
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| ISSN: | 03014738 19983689 |
|---|---|
| DOI: | 10.4103/IJO.IJO_1700_23 |
| Published in: | Indian Journal of Ophthalmology |
| Language: | English |