Polypharmacy and Therapeutic Inertia in Extreme Longevity: A Potential Clinical Ageism Scenario Secondary to Important Gaps in Clinical Evidence
| Title: | Polypharmacy and Therapeutic Inertia in Extreme Longevity: A Potential Clinical Ageism Scenario Secondary to Important Gaps in Clinical Evidence |
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| Authors: | María Viviana Pantoja, Ivan David Lozada-Martinez |
| Source: | Journal of Preventive Medicine and Public Health, Vol 57, Iss 5, Pp 508-510 (2024) |
| Publisher Information: | Korean Society for Preventive Medicine, 2024. |
| Publication Year: | 2024 |
| Collection: | LCC:Medicine LCC:Public aspects of medicine |
| Subject Terms: | nonagenarians, centenarians, polypharmacy, ageism, secondary prevention, Medicine, Public aspects of medicine, RA1-1270 |
| More Details: | Population aging is a global health priority due to the dramatic increase in the proportion of older persons worldwide. It is also expected that both global life expectancy and disability-free life expectancy will increase, leading to a significant rise in the proportion of individuals with extreme longevity, such as non-agenarians and centenarians. The inaccuracy of clinical evidence on therapeutic interventions for this demographic could lead to biased decision-making, influenced by age-related beliefs or misperceptions about their therapeutic needs. This represents a potential clinical ageism scenario stemming from gaps in clinical evidence. Such biases can result in 2 significant issues that adversely affect the health status and prognosis of older persons: polypharmacy and therapeutic inertia. To date, documents on polypharmacy in non-agenarians and centenarians account for less than 0.35% of the overall available evidence on polypharmacy. Furthermore, evidence regarding therapeutic inertia is non-existent. The purpose of this letter is to discuss polypharmacy and therapeutic inertia as potential clinical ageism scenarios resulting from the clinical evidence gaps in extreme longevity. |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English |
| ISSN: | 1975-8375 2233-4521 |
| Relation: | http://jpmph.org/upload/pdf/jpmph-24-364.pdf; https://doaj.org/toc/1975-8375; https://doaj.org/toc/2233-4521 |
| DOI: | 10.3961/jpmph.24.364 |
| Access URL: | https://doaj.org/article/97d1bbb7908b439baeb66e12e08a530e |
| Accession Number: | edsdoj.97d1bbb7908b439baeb66e12e08a530e |
| Database: | Directory of Open Access Journals |
| ISSN: | 19758375 22334521 |
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| DOI: | 10.3961/jpmph.24.364 |
| Published in: | Journal of Preventive Medicine and Public Health |
| Language: | English |