Intrauterine transmission of SARS-CoV-2 to and prenatal ultrasound abnormal findings in the fetus of a pregnant woman with mild COVID-19

Bibliographic Details
Title: Intrauterine transmission of SARS-CoV-2 to and prenatal ultrasound abnormal findings in the fetus of a pregnant woman with mild COVID-19
Authors: Meixiang Zhang, Liqiong Hou, Liangyu Guo, Qichang Zhou, Hougang Zhou, Na Sang, Ting Tan, Yan Xie, Yongjun Wang, Xiaoliang Huang, Jing Liu, Chunwang Li, Beilei Huang, Yulin Peng, Yifan Kong, Yingchun Luo
Source: BMC Pregnancy and Childbirth, Vol 23, Iss 1, Pp 1-7 (2023)
Publisher Information: BMC, 2023.
Publication Year: 2023
Collection: LCC:Gynecology and obstetrics
Subject Terms: COVID-19, Intrauterine transmission, Fetal abnormal ultrasound findings, Gynecology and obstetrics, RG1-991
More Details: Abstract Background Whether intrauterine transmission of COVID-19 occurs remains uncertain, and it remains unclear whether the disease affects fetuses. We present a case of intrauterine transmission of SARS-CoV-2 infection and the prenatal ultrasonographic findings of the fetus in a pregnant woman with mild COVID-19. Case presentation A 30-year-old woman was admitted to our hospital for ultrasound examination in January 2023 at 26+ 3 weeks’ gestation. Twenty-one days prior, her COVID-19 nucleic acid test was positive, and she had mild symptoms, including fever (38.3 °C), headache, chills, ankle pain and cough. After receiving symptomatic treatment, she fully recovered. Prenatal ultrasound revealed that the placenta was diffusely distributed with punctate echogenic foci, hepatomegaly, and the volume of bilateral lungs decreased significantly, with enhanced echo. In addition, we found that the surface of the fetal brain demonstrated widened gyri with a flattened surface. The prenatal MRI confirmed these fetal abnormalities. Amniotic fluid was tested for SARS-CoV-2, and the sample tested was positive for the virus. After careful consideration, the pregnant woman decided to terminate the pregnancy. Conclusion The intrauterine transmission of COVID-19 is certain. Moreover, the intrauterine transmission of COVID-19 may cause abnormalities in various organs of the fetus.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 1471-2393
Relation: https://doaj.org/toc/1471-2393
DOI: 10.1186/s12884-023-06053-y
Access URL: https://doaj.org/article/9766c302afb14b1f91bc40509dcd3824
Accession Number: edsdoj.9766c302afb14b1f91bc40509dcd3824
Database: Directory of Open Access Journals
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More Details
ISSN:14712393
DOI:10.1186/s12884-023-06053-y
Published in:BMC Pregnancy and Childbirth
Language:English