Bibliographic Details
| Title: |
Tumor budding may be a promising prognostic indicator in intrahepatic cholangiocarcinoma: A multicenter retrospective study |
| Authors: |
Hisashi Kosaka, Mitsuaki Ishida, Masaki Ueno, Koji Komeda, Daisuke Hokutou, Hiroya Iida, Fumitoshi Hirokawa, Kosuke Matsui, Mitsugu Sekimoto, Masaki Kaibori |
| Source: |
Annals of Gastroenterological Surgery, Vol 7, Iss 1, Pp 138-146 (2023) |
| Publisher Information: |
Wiley, 2023. |
| Publication Year: |
2023 |
| Collection: |
LCC:Surgery
LCC:Diseases of the digestive system. Gastroenterology |
| Subject Terms: |
cancer staging, intrahepatic bile duct, intrahepatic cholangiocarcinoma, TNM classification, tumor staging, Surgery, RD1-811, Diseases of the digestive system. Gastroenterology, RC799-869 |
| More Details: |
Abstract Purpose This retrospective study evaluated our hypothesis that high tumor budding (≥10 buds) may help determine the appropriate T category for more accurate staging of intrahepatic cholangiocarcinoma (ICC). Methods We analyzed the clinical and histopathologic data of 235 consecutive patients with histologically confirmed ICC following hepatectomy at five university hospitals in the Kansai region of Japan between January 2009 and December 2020. ICC staging was based on the Liver Cancer Study Group of Japan (LCSGJ) staging system, 6th edition. Results Patients with ICC with high budding showed significantly shorter disease‐specific survival (DSS) and disease‐free survival (DFS) than patients with low/intermediate budding. Cox proportional hazards regression analysis showed a hazard ratio of 2.2‐2.3 (P |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2475-0328 |
| Relation: |
https://doaj.org/toc/2475-0328 |
| DOI: |
10.1002/ags3.12605 |
| Access URL: |
https://doaj.org/article/97534828836744059eda4acfc311e7d1 |
| Accession Number: |
edsdoj.97534828836744059eda4acfc311e7d1 |
| Database: |
Directory of Open Access Journals |
