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Resistive index of central retinal artery, aortic arterial stiffness and OCTA correlated parameters in the early stage of fabry disease

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Title: Resistive index of central retinal artery, aortic arterial stiffness and OCTA correlated parameters in the early stage of fabry disease
Authors: Michele Rinaldi, Flavia Chiosi, Maria Laura Passaro, Francesco Natale, Alessia Riccardo, Luca D’Andrea, Martina Caiazza, Marta Rubino, Emanuele Monda, Gilda Cennamo, Francesco Calabrò, Giuseppe Limongelli, Ciro Costagliola
Source: Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Publisher Information: Nature Portfolio, 2024.
Publication Year: 2024
Collection: LCC:Medicine
LCC:Science
Subject Terms: Fabry disease, Retinal vessel density, Retinal and choroidal microangiopathy, OCT angiography, Resistive index of central retinal artery, Medicine, Science
More Details: Abstract This study aimed to evaluate the impact of Fabry disease (FD) on retinal microvasculature using optical coherence tomography angiography (OCTA), arterial stiffness, and the resistive index (RI) of the central retinal artery (CRA) in early disease stages. Twenty-nine genetically confirmed FD patients and twenty-six healthy controls were enrolled. Vessel density (VD) values of the superficial, deep, and choriocapillaris plexuses (SCP, DCP, and CC) were measured via OCTA. CRA RI was studied using color Doppler and grayscale sonography, and aortic pulse wave velocity (PWV) was assessed with the Complior method. CRA RI was significantly lower in the control group compared to the Fabry group (p
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2045-2322
Relation: https://doaj.org/toc/2045-2322
DOI: 10.1038/s41598-024-74146-5
Access URL: https://doaj.org/article/96b0aaf653bd4ae78f1232f689b26f53
Accession Number: edsdoj.96b0aaf653bd4ae78f1232f689b26f53
Database: Directory of Open Access Journals
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More Details
ISSN:20452322
DOI:10.1038/s41598-024-74146-5
Published in:Scientific Reports
Language:English