Full Text from JSTOR Exposure to loud noise and risk of vestibular schwannoma: results from the INTERPHONE international case‒control study
| Title: | Exposure to loud noise and risk of vestibular schwannoma: results from the INTERPHONE international case‒control study |
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| Authors: | Isabelle Deltour, Brigitte Schlehofer, Amélie Massardier-Pilonchéry, Klaus Schlaefer, Bruce Armstrong, Graham G Giles, Jack Siemiatycki, Marie-Elise Parent, Daniel Krewski, Mary McBride, Christoffer Johansen, Anssi Auvinen, Tiina Salminen, Martine Hours, Lucile Montestrucq, Maria Blettner, Gabriele Berg-Beckhoff, Siegal Sadetzki, Angela Chetrit, Susanna Lagorio, Ivano Iavarone, Naohito Yamaguchi, Toru Takebayashi, Alistair Woodward, Angus Cook, Tore Tynes, Lars Klaeboe, Maria Feychting, Stefan Lönn, Sarah Fleming, Anthony J Swerdlow, Minouk J Schoemaker, Monika Moissonnier, Ausrele Kesminiene, Elisabeth Cardis, Joachim Schüz, INTERPHONE Study Group |
| Source: | Scandinavian Journal of Work, Environment & Health, Vol 45, Iss 2, Pp 183-193 (2019) |
| Publisher Information: | Nordic Association of Occupational Safety and Health (NOROSH), 2019. |
| Publication Year: | 2019 |
| Collection: | LCC:Public aspects of medicine |
| Subject Terms: | vestibular schwannoma, interphone, case‒control study, acoustic neuroma, epidemiology, exposure, noise, noise exposure, international, loud noise, Public aspects of medicine, RA1-1270 |
| More Details: | OBJECTIVE: Studies of loud noise exposure and vestibular schwannomas (VS) have shown conflicting results. The population-based INTERPHONE case‒control study was conducted in 13 countries during 2000–2004. In this paper, we report the results of analyses on the association between VS and self-reported loud noise exposure. METHODS: Self-reported noise exposure was analyzed in 1024 VS cases and 1984 matched controls. Life-long noise exposure was estimated through detailed questions. Odds ratios (OR) and 95% confidence intervals (CI) were estimated using adjusted conditional logistic regression for matched sets. RESULTS: The OR for total work and leisure noise exposure was 1.6 (95% CI 1.4–1.9). OR were 1.5 (95% CI 1.3–1.9) for only occupational noise, 1.9 (95% CI 1.4–2.6) for only leisure noise and 1.7 (95% CI 1.2–2.2) for exposure in both contexts. OR increased slightly with increasing lag-time. For occupational exposures, duration, time since exposure start and a metric combining lifetime duration and weekly exposure showed significant trends of increasing risk with increasing exposure. OR did not differ markedly by source or other characteristics of noise. CONCLUSION: The consistent associations seen are likely to reflect either recall bias or a causal association, or potentially indicate a mixture of both. |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English |
| ISSN: | 0355-3140 1795-990X |
| Relation: | https://www.sjweh.fi/show_abstract.php?abstract_id=3781; https://doaj.org/toc/0355-3140; https://doaj.org/toc/1795-990X |
| DOI: | 10.5271/sjweh.3781 |
| Access URL: | https://doaj.org/article/a95c99eec42e473b90ad6ef55a78193e |
| Accession Number: | edsdoj.95c99eec42e473b90ad6ef55a78193e |
| Database: | Directory of Open Access Journals |
| ISSN: | 03553140 1795990X |
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| DOI: | 10.5271/sjweh.3781 |
| Published in: | Scandinavian Journal of Work, Environment & Health |
| Language: | English |