Bibliographic Details
| Title: |
Adverse Reactions after Administration of Antivenom in Korea |
| Authors: |
Jin Seok Shim, Hyunggoo Kang, Yongil Cho, Hyungoo Shin, Heekyung Lee |
| Source: |
Toxins, Vol 12, Iss 8, p 507 (2020) |
| Publisher Information: |
MDPI AG, 2020. |
| Publication Year: |
2020 |
| Collection: |
LCC:Medicine |
| Subject Terms: |
snake venom, antivenom, adverse reaction, snakebite, Medicine |
| More Details: |
Kovax® antivenom is the main treatment for toxins produced by the Gloydius species. However, research on adverse reactions after Kovax® antivenom administration is scarce. We aimed to identify the incidence and characteristics of adverse reactions after Kovax® antivenom administration. We conducted a retrospective review of the medical records of snakebite patients in Korea between January 2008 and September 2019. We identified the frequency, characteristics, and treatments of adverse reactions to Kovax® antivenom. There were 150 patients with snakebites, of whom 121 (80.7%) patients received Kovax® antivenom. Adverse reactions occurred in five patients (4.1%). Acute adverse reactions within 24 h of antivenom administration occurred in two patients (1.7%). The symptoms of patients with acute adverse reactions were nausea, diaphoresis, dizziness, and hypotension. Delayed adverse reactions that occurred 24 h after antivenom administration were reported in three patients (2.5%). One patient had a skin rash after 10 days, and two patients had fever 37 and 48 h after antivenom use. In conclusion, most patients were managed safely after Kovax® antivenom, and the incidence of adverse reactions was low. Severe adverse reactions occurred in a small percentage of patients, and there were no deaths. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2072-6651 |
| Relation: |
https://www.mdpi.com/2072-6651/12/8/507; https://doaj.org/toc/2072-6651 |
| DOI: |
10.3390/toxins12080507 |
| Access URL: |
https://doaj.org/article/94abf012d27a4ffa95e839448ae09fdf |
| Accession Number: |
edsdoj.94abf012d27a4ffa95e839448ae09fdf |
| Database: |
Directory of Open Access Journals |
