Effects ofprognostic parameters and radiotherapy on survival of patients with pulmonary cancer
| Title: | Effects ofprognostic parameters and radiotherapy on survival of patients with pulmonary cancer |
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| Authors: | E Yuozaitite, A Inchura, R Sakalauskas, L Valius |
| Source: | Терапевтический архив, Vol 79, Iss 10, Pp 17-22 (2004) |
| Publisher Information: | "Consilium Medicum" Publishing house, 2004. |
| Publication Year: | 2004 |
| Collection: | LCC:Medicine |
| Subject Terms: | pulmonary cancer, threedimentional conformic radiotherapy, prognostic factors, survival, Medicine |
| More Details: | Aim. To analyze factors influencing expected survival of pulmonary cancer (PC) patients given radiotherapy, i.e. age of the patient, stage of the disease, size of the tumor, involvement of the lymph nodes, a total focal dose, space distribution of the dose. Material and methods. Among PC patients 87% were males and 73.9% were 60 years of age and older. Local PC (stage Ilia and IUb) was diagnosed in 65.2%. Non-small-cell PC was in 83.8%. Effects of radiotherapy on the survival was analysed in 115 patients. Total focal doses made up 30 Gy (3.0 Gy/10fractions) to 70 Gy (2.0 Gy/35fractions). Results. Longer survival was achieved after irradiation with greater dose and modern three-dimentional planning ofconformic radiotherapy. A significant prolongation of the survival was seen in raising the total focal dose to 50 Gy. There is a correlation between the dose and conformity of the dose distribution. During the study 58.2% patients died. Conclusion. Assessment of the survival of PC patients given radiotherapy has shown that negative prognostic factors are the following: PC stage IIIA, IHB and IV, extensive local spread of the tumor, large primary tumor, involvement of the lymph nodes. |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | Russian |
| ISSN: | 0040-3660 2309-5342 |
| Relation: | https://ter-arkhiv.ru/0040-3660/article/view/29884; https://doaj.org/toc/0040-3660; https://doaj.org/toc/2309-5342 |
| Access URL: | https://doaj.org/article/dd940d1522a14cc88d6158f6b5212545 |
| Accession Number: | edsdoj.940d1522a14cc88d6158f6b5212545 |
| Database: | Directory of Open Access Journals |
| ISSN: | 00403660 23095342 |
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| Published in: | Терапевтический архив |
| Language: | Russian |