Thick artery–artery anastomoses delay the onset of selective fetal growth restriction in monochorionic diamniotic twins: a 7-year single-center cohort study
| Title: | Thick artery–artery anastomoses delay the onset of selective fetal growth restriction in monochorionic diamniotic twins: a 7-year single-center cohort study |
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| Authors: | Xueju Wang, Luyao Li, Pengbo Yuan, Yangyu Zhao, Yuan Wei |
| Source: | Frontiers in Medicine, Vol 10 (2023) |
| Publisher Information: | Frontiers Media S.A., 2023. |
| Publication Year: | 2023 |
| Collection: | LCC:Medicine (General) |
| Subject Terms: | selective fetal growth restriction, onset time, placental territory, vascular anastomosis, monochorionic diamniotic twins, Medicine (General), R5-920 |
| More Details: | ObjectiveThis study aimed to investigate differences in placental characteristics between early- and late-onset selective fetal growth restriction (sFGR) in monochorionic diamniotic twins.MethodsA total of 253 patients with sFGR between April 2013 and April 2020 were retrospectively analyzed. Placental characteristics of early- and late-onset sFGR were compared.ResultsThe gestational age at diagnosis and delivery in the early-onset group was significantly less than that in the late-onset group [22.0 (16.9–23.9) and 28.4 (24.0, 36.3) weeks, P < 0.001; 33.1 ± 2.2 and 33.7 ± 2.5 weeks, P = 0.025]. The birth weight of normal growth and growth-restricted fetuses in the early-onset group was less than the late-onset group [1,990 ± 422 and 2,162 ± 525 g, P = 0.044; 1,320 ± 409 and 1,595 ± 519 g, P = 0.001]. The birthweight discordance ratio in the early-onset group was greater than the late-onset group (0.34 ± 0.12 and 0.29 ± 0.13, P = 0.001). The early-onset group had a significantly lower prevalence of sFGR type I than the late-onset group (37.5 and 62.0%, P = 0.018). The early-onset group had a significantly higher prevalence of sFGR type III than the late-onset group (30.4 and 12.7%, P = 0.048). The early-onset group had a lower prevalence of thick artery–artery anastomoses than the late-onset group (37.5 and 62.0%, P = 0.006). The placental territory discordance ratio in the early-onset group was higher than in the late-onset group [0.60 (0.01, 0.80) and 0.50 (0.01, 0.88), P = 0.018].ConclusionUnequal placental territory is the cause for most of the late-onset sFGR. Thick artery–artery anastomoses may delay the onset time of these cases of sFGR. |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English |
| ISSN: | 2296-858X 56150989 |
| Relation: | https://www.frontiersin.org/articles/10.3389/fmed.2023.1265875/full; https://doaj.org/toc/2296-858X |
| DOI: | 10.3389/fmed.2023.1265875 |
| Access URL: | https://doaj.org/article/d93086fae0da433280a561509890fe51 |
| Accession Number: | edsdoj.93086fae0da433280a561509890fe51 |
| Database: | Directory of Open Access Journals |
| ISSN: | 2296858X 56150989 |
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| DOI: | 10.3389/fmed.2023.1265875 |
| Published in: | Frontiers in Medicine |
| Language: | English |