Bibliographic Details
| Title: |
Association between stress hyperglycemia ratio and contrast-induced nephropathy in ACS patients undergoing PCI: a retrospective cohort study from the MIMIC-IV database |
| Authors: |
Yanlong Zhao, Yuanyuan Zhao, Shuai Wang, Zhenxing Fan, Yanling Wang, Fangyan Liu, Zhi Liu |
| Source: |
BMC Cardiovascular Disorders, Vol 25, Iss 1, Pp 1-14 (2025) |
| Publisher Information: |
BMC, 2025. |
| Publication Year: |
2025 |
| Collection: |
LCC:Diseases of the circulatory (Cardiovascular) system |
| Subject Terms: |
Stress hyperglycemia ratio, Contrast-induced nephropathy, Acute coronary syndrome, Percutaneous coronary intervention, Short-term mortality, Diseases of the circulatory (Cardiovascular) system, RC666-701 |
| More Details: |
Abstract Background Contrast-induced nephropathy (CIN) is a significant complication in acute coronary syndrome (ACS) patients undergoing percutaneous coronary intervention (PCI). The role of the stress hyperglycemia ratio (SHR) as a predictor of CIN and mortality in these patients remains unclear and warrants investigation. Objective To assess the relationship between SHR and CIN, as well as its impact on short-term mortality in ACS patients undergoing PCI. Methods We conducted a retrospective cohort study using the MIMIC-IV database, including 552 ACS patients. SHR was calculated as the ratio of admission glucose to estimated average glucose from hemoglobin A1c. CIN was defined as a ≥ 0.5 mg/dL or ≥ 25% increase in serum creatinine within 48 h of PCI. Logistic regression and spline models were used to analyze the association between SHR and CIN, while Kaplan–Meier curves assessed 30-day mortality. Results Higher SHR levels were independently associated with increased CIN risk (OR 2.36, 95% CI: 1.56–3.57, P |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
1471-2261 |
| Relation: |
https://doaj.org/toc/1471-2261 |
| DOI: |
10.1186/s12872-025-04573-3 |
| Access URL: |
https://doaj.org/article/9291bd76fe67473d9a4252d924dcb8d1 |
| Accession Number: |
edsdoj.9291bd76fe67473d9a4252d924dcb8d1 |
| Database: |
Directory of Open Access Journals |
