Bibliographic Details
| Title: |
Rapid analysis of fifteen sulfonamide residues in pork and fish samples by automated on-line solid phase extraction coupled to liquid chromatography–tandem mass spectrometry |
| Authors: |
Junmei Ma, Sufang Fan, Lei Sun, Liangna He, Yan Zhang, Qiang Li |
| Source: |
Food Science and Human Wellness, Vol 9, Iss 4, Pp 363-369 (2020) |
| Publisher Information: |
Tsinghua University Press, 2020. |
| Publication Year: |
2020 |
| Collection: |
LCC:Nutrition. Foods and food supply |
| Subject Terms: |
Liquid chromatography–tandem mass spectrometry, On-line solid phase extraction, Sulfonamides, Internal standard quantification, Nutrition. Foods and food supply, TX341-641 |
| More Details: |
The aim of this work was to develop an automated on-line solid phase extraction (SPE) with liquid chromatography-tandem mass spectrometry method for the detection of fifteen sulfonamides in pork and fish samples. Samples were extracted with 0.2% formic acid acetonitrile solution, purified by on-line SPE device with HLB column, then separated by XBridge C18 column, using 0.1% formic acid solution and acetonitrile as the mobile phase. Mass spectrometric data was acquired under multiple reaction monitoring (MRM) mode using positive ionization electrospray. Internal standard method was used in the quantification, good linear relationship was got in range of 0.1–100 ng/mL and correlation coefficient was higher than 0.9990. The limits of detection were in the range of 0.125–2.00 μg/kg and the limits of quantitation were in the range of 0.250–5.00 μg/kg. Recoveries of the method were in range of 78.3%–99.3%, relative standard deviation were lower than 10%. The method was simple, sensitivity, and could be used for routine supervision and analysis of fifteen sulfonamides in pork and fish. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2213-4530 |
| Relation: |
http://www.sciencedirect.com/science/article/pii/S2213453020301415; https://doaj.org/toc/2213-4530 |
| DOI: |
10.1016/j.fshw.2020.05.002 |
| Access URL: |
https://doaj.org/article/920d904a853b438c965a2992d529701e |
| Accession Number: |
edsdoj.920d904a853b438c965a2992d529701e |
| Database: |
Directory of Open Access Journals |
