Case report: Cutaneous pseudolymphoma caused by a Leishmania infantum infection in a patient treated with anti-TNF antibody for plaque psoriasis

Bibliographic Details
Title: Case report: Cutaneous pseudolymphoma caused by a Leishmania infantum infection in a patient treated with anti-TNF antibody for plaque psoriasis
Authors: Sarah Scholl, Daniel Schuster, Kristin Technau-Hafsi, Katarina Stete, Siegbert Rieg, Annette M. May, Christian Bogdan, Franziska Schauer
Source: Frontiers in Medicine, Vol 9 (2022)
Publisher Information: Frontiers Media S.A., 2022.
Publication Year: 2022
Collection: LCC:Medicine (General)
Subject Terms: skin pseudolymphoma, cutaneous leishmaniasis, anti-TNF therapy, adalimumab, skin ulceration, Medicine (General), R5-920
More Details: For psoriasis, which affects up to 2% of the population and adalimumab is approved from the age of 4 years. Here, we present a middle-aged Italian man with long-term history of plaque psoriasis and psoriasis arthropathica and adalimumab therapy. He developed ulcers or nodules within the psoriatic plaques, resembling cutaneous infection with Leishmania infantum. TNF and other cytokines such as IL-12 and IFN-γ are central in the early control of the infection. Discontinuation of the anti-TNF-treatment resolved the infection without specific therapy.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2296-858X
Relation: https://www.frontiersin.org/articles/10.3389/fmed.2022.1055703/full; https://doaj.org/toc/2296-858X
DOI: 10.3389/fmed.2022.1055703
Access URL: https://doaj.org/article/911921c3be2240708871ba5b3efb79f3
Accession Number: edsdoj.911921c3be2240708871ba5b3efb79f3
Database: Directory of Open Access Journals
More Details
ISSN:2296858X
DOI:10.3389/fmed.2022.1055703
Published in:Frontiers in Medicine
Language:English