Bibliographic Details
| Title: |
Paper-Based Immunosensors with Bio-Chemiluminescence Detection |
| Authors: |
Maria Maddalena Calabretta, Martina Zangheri, Donato Calabria, Antonia Lopreside, Laura Montali, Elisa Marchegiani, Ilaria Trozzi, Massimo Guardigli, Mara Mirasoli, Elisa Michelini |
| Source: |
Sensors, Vol 21, Iss 13, p 4309 (2021) |
| Publisher Information: |
MDPI AG, 2021. |
| Publication Year: |
2021 |
| Collection: |
LCC:Chemical technology |
| Subject Terms: |
paper-based, bio-chemiluminescence, immunosensor, biosensor, point-of-care, Chemical technology, TP1-1185 |
| More Details: |
Since the introduction of paper-based analytical devices as potential diagnostic platforms a few decades ago, huge efforts have been made in this field to develop systems suitable for meeting the requirements for the point-of-care (POC) approach. Considerable progress has been achieved in the adaptation of existing analysis methods to a paper-based format, especially considering the chemiluminescent (CL)-immunoassays-based techniques. The implementation of biospecific assays with CL detection and paper-based technology represents an ideal solution for the development of portable analytical devices for on-site applications, since the peculiarities of these features create a unique combination for fitting the POC purposes. Despite this, the scientific production is not paralleled by the diffusion of such devices into everyday life. This review aims to highlight the open issues that are responsible for this discrepancy and to find the aspects that require a focused and targeted research to make these methods really applicable in routine analysis. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
1424-8220 |
| Relation: |
https://www.mdpi.com/1424-8220/21/13/4309; https://doaj.org/toc/1424-8220 |
| DOI: |
10.3390/s21134309 |
| Access URL: |
https://doaj.org/article/906d4c7bbfb7413cb090329e6efe6a19 |
| Accession Number: |
edsdoj.906d4c7bbfb7413cb090329e6efe6a19 |
| Database: |
Directory of Open Access Journals |
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