| Title: |
Pre-activation of autophagy impacts response to olaparib in prostate cancer cells |
| Authors: |
Maxime Cahuzac, Patricia Langlois, Benjamin Péant, Hubert Fleury, Anne-Marie Mes-Masson, Fred Saad |
| Source: |
Communications Biology, Vol 5, Iss 1, Pp 1-14 (2022) |
| Publisher Information: |
Nature Portfolio, 2022. |
| Publication Year: |
2022 |
| Collection: |
LCC:Biology (General) |
| Subject Terms: |
Biology (General), QH301-705.5 |
| More Details: |
Pre-activation of autophagy mediates resistance to olaparib by decreasing nuclear SQSTM1/p62, which increases homologous recombination-mediated repair through filamin A expression and BRCA1/Rad51 recruitment. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2399-3642 |
| Relation: |
https://doaj.org/toc/2399-3642 |
| DOI: |
10.1038/s42003-022-03210-5 |
| Access URL: |
https://doaj.org/article/90493fedb1da4a0c9ce515338e9d1823 |
| Accession Number: |
edsdoj.90493fedb1da4a0c9ce515338e9d1823 |
| Database: |
Directory of Open Access Journals |
