Bibliographic Details
| Title: |
The association of 'Neurofibromatosis-1, congenital pseudarthrosis of the Tibia and type 1 DM' report of two cases and literature review |
| Authors: |
Mahmoud A. El-Rosasy, Abdullah Khaled, Amr M. Elrosasy, Heba Dawoud |
| Source: |
Journal of Orthopaedic Reports, Vol 4, Iss 1, Pp 100378- (2025) |
| Publisher Information: |
Elsevier, 2025. |
| Publication Year: |
2025 |
| Collection: |
LCC:Orthopedic surgery |
| Subject Terms: |
Orthopedic surgery, RD701-811 |
| More Details: |
Background: Neurofibromatosis type 1 (NF1) is a relatively common disorder and is typically diagnosed clinically. NF1 is commonly associated with different autoimmune diseases. The association between NF1 and Type 1DM is rarely reported in the literature. Case: We are presenting the first report of two children who are known to have Neurofibromatosis-1 and congenital pseudarthrosis of the tibia and during their treatment, they developed type 1 DM. Conclusion: Neurofibromatosis-1 is a multi-systemic disorder, and its management involves various medical and surgical specialties. Before embarking on major limb reconstruction for CPT, the Orthopaedic surgeon is requested to consider other systemic involvements. A high suspicion index should draw the attention of the treating surgeon in case the child develops any symptoms or signs suggestive of any systemic disorder. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2773-157X |
| Relation: |
http://www.sciencedirect.com/science/article/pii/S2773157X24000730; https://doaj.org/toc/2773-157X |
| DOI: |
10.1016/j.jorep.2024.100378 |
| Access URL: |
https://doaj.org/article/a903e58df4f446468fbbe8f1ea669065 |
| Accession Number: |
edsdoj.903e58df4f446468fbbe8f1ea669065 |
| Database: |
Directory of Open Access Journals |
