Bibliographic Details
| Title: |
New Cyclic Pentapeptides from the Mangrove-Derived Aspergillus fumigatus GXIMD 03099 |
| Authors: |
Yu Wang, Guangping Cao, Yuman Gan, Xiao Lin, Xiangxi Yi, Longyan Zhao, Yonghong Liu, Chenghai Gao, Meng Bai |
| Source: |
Marine Drugs, Vol 22, Iss 6, p 282 (2024) |
| Publisher Information: |
MDPI AG, 2024. |
| Publication Year: |
2024 |
| Collection: |
LCC:Biology (General) |
| Subject Terms: |
mangrove-derived fungus, Aspergillus fumigatus, cyclic pentapeptides, biological activity, Biology (General), QH301-705.5 |
| More Details: |
Four new cyclic pentapeptides, avellanins D–G (1–4), together with four known compounds (5–8), were isolated from a mangrove-derived Aspergillus fumigatus GXIMD 03099 fungus from Acanthus ilicifolius L. Their structures were elucidated by analysis of HRESIMS, NMR, and ESI-MS/MS data. Their absolute configurations were determined by X-ray diffraction analysis and Marfey’s method. Compounds 1–8 were screened for insecticidal and antibacterial activities. Compound 2 showed insecticidal activity against newly hatched larvae of Culex quinquefasciatus with an LC50 value of 86.6 µM; compound 4 had weak activity against Vibrio harveyi with an MIC value of 5.85 µM. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
1660-3397 |
| Relation: |
https://www.mdpi.com/1660-3397/22/6/282; https://doaj.org/toc/1660-3397 |
| DOI: |
10.3390/md22060282 |
| Access URL: |
https://doaj.org/article/901d7ff4b111427c8430621f2a158184 |
| Accession Number: |
edsdoj.901d7ff4b111427c8430621f2a158184 |
| Database: |
Directory of Open Access Journals |
