Bibliographic Details
| Title: |
Abnormal Granger causal connectivity based on altered gray matter volume and associated neurotransmitters of adolescents with internet gaming disorder revealed by a multimodal neuroimaging study |
| Authors: |
Xiaoyu Niu, Mengzhe Zhang, Xinyu Gao, Jinghan Dang, Jieping Sun, Qiuying Tao, Yan Lang, Weijian Wang, Yarui Wei, Shaoqiang Han, Huayan Xu, Yingkun Guo, Jingliang Cheng, Yong Zhang |
| Source: |
Developmental Cognitive Neuroscience, Vol 70, Iss , Pp 101472- (2024) |
| Publisher Information: |
Elsevier, 2024. |
| Publication Year: |
2024 |
| Collection: |
LCC:Neurophysiology and neuropsychology |
| Subject Terms: |
Internet gaming disorder (IGD), Adolescents, Gray matter volume (GMV), Voxel-based morphometry (VBM), Granger causality analysis (GCA), Neurotransmitter, Neurophysiology and neuropsychology, QP351-495 |
| More Details: |
Although prior studies have revealed alterations in gray matter volume (GMV) among individuals with internet gaming disorder (IGD). The brain's multifaceted functions hinge crucially on the intricate connections and communication among distinct regions. However, the intricate interaction of information between brain regions with altered GMV and other regions, and how they synchronize with various neurotransmitter systems, remains enigmatic. Therefore, we aimed to integrate structural, functional and molecular data to explore the GMV-based Granger causal connectivity abnormalities and their correlated neurotransmitter systems in IGD adolescents. Voxel-based morphometry (VBM) analysis was firstly performed to investigate GMV differences between 37 IGD adolescents and 35 matched controls. Brain regions with altered GMV were selected as seeds for further Granger causality analysis (GCA). Two-sample t tests were performed using the SPM12 toolkit to compare the GMV and Granger causal connectivity between IGD and control groups (GRF corrected, Pvoxel |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
1878-9293 |
| Relation: |
http://www.sciencedirect.com/science/article/pii/S1878929324001336; https://doaj.org/toc/1878-9293 |
| DOI: |
10.1016/j.dcn.2024.101472 |
| Access URL: |
https://doaj.org/article/8fe29e47aeae4243931f75f8c8cfec46 |
| Accession Number: |
edsdoj.8fe29e47aeae4243931f75f8c8cfec46 |
| Database: |
Directory of Open Access Journals |
