Bibliographic Details
| Title: |
Higher hemoglobin levels are associated with impaired left ventricular global strains in metabolic syndrome: a 3.0 T CMR feature tracking study |
| Authors: |
Xue Li, Shi-Qin Yu, Zhi-Gang Yang, Bi-Yue Hu, Ke Shi, Jing Wang, Xue-Ming Li, Ge Zhang, Wen-Rong Li, Rong Xu, Yuan Li |
| Source: |
Cardiovascular Diabetology, Vol 24, Iss 1, Pp 1-11 (2025) |
| Publisher Information: |
BMC, 2025. |
| Publication Year: |
2025 |
| Collection: |
LCC:Diseases of the circulatory (Cardiovascular) system |
| Subject Terms: |
Cardiac magnetic resonance, Hemoglobin levels, Left ventricular strain, Metabolic syndrome, Obesity, Diseases of the circulatory (Cardiovascular) system, RC666-701 |
| More Details: |
Abstract Background Metabolic syndrome (MetS) is a known contributor to increased cardiovascular risk and all-cause mortality. Recent literatures suggested that higher hemoglobin (Hb) levels were associated with Mets, left ventricular (LV) dysfunction and adverse events in general population. This study aimed to assess the associations between Hb levels and LV global strains in patients with MetS. Methods A retrospective analysis included 254 patients with MetS and 78 sex-, age-, and Hb-matched controls. The MetS patients were stratified into five groups based on Hb levels: anemia, low-normal Hb, moderate-normal Hb, high-normal Hb, and high Hb. LV global radial, circumferential, and longitudinal strains (LVGRS, LVGCS, and LVGLS, respectively) were measured using the cardiac magnetic resonance feature tracking technique. Associations between Hb levels and LV global strains were evaluated using multiple linear regression, restricted cubic spline (RCS), and subgroup analyses. Results After full adjustment, the LV global strains from three directions in the high Hb groups (LVGRS: β = − 4.943, 95% CI − 7.673 to − 2.213; LVGCS: β = − 2.341, 95% CI − 3.608 to − 1.074; LVGLS: β = −2.797, 95% CI − 4.049 to − 1.546, all p |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
1475-2840 |
| Relation: |
https://doaj.org/toc/1475-2840 |
| DOI: |
10.1186/s12933-025-02664-1 |
| Access URL: |
https://doaj.org/article/8fa20f011dc341908f9b7df319e00468 |
| Accession Number: |
edsdoj.8fa20f011dc341908f9b7df319e00468 |
| Database: |
Directory of Open Access Journals |
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