Age of onset correlates with clinical characteristics and prognostic outcomes in neuromyelitis optica spectrum disorder

Bibliographic Details
Title: Age of onset correlates with clinical characteristics and prognostic outcomes in neuromyelitis optica spectrum disorder
Authors: Yacen Hu, Qiying Sun, Fang Yi, Lingyan Yao, Yun Tian, Haiyun Tang, Mengchuan Luo, Nina Xie, Zhiqin Wang, Xinxin Liao, Lin Zhou, Hongwei Xu, Yafang Zhou
Source: Frontiers in Immunology, Vol 13 (2022)
Publisher Information: Frontiers Media S.A., 2022.
Publication Year: 2022
Collection: LCC:Immunologic diseases. Allergy
Subject Terms: neuromyelitis optica spectrum disorder, late-onset NMOSD, age of onset, clinical characteristic, prognosis, Immunologic diseases. Allergy, RC581-607
More Details: ObjectiveNeuromyelitis optica spectrum disorder (NMOSD) is an inflammatory disease preferentially affects the optic nerve and the spinal cord. The first attack usually occurs in the third or fourth decade, though patients with disease onset in the fifties or later are not uncommon. This study aimed to investigate the clinical characteristics and prognosis in patients with different age of onset and to explore the correlations between age of onset and clinical characteristics and prognostic outcomes.MethodWe retrospectively reviewed the medical records of 298 NMOSD patients diagnosed according to the 2015 updated version of diagnostic criteria. Patients were divided into early-onset NMOSD (EO-NMOSD) (
Document Type: article
File Description: electronic resource
Language: English
ISSN: 1664-3224
Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2022.1056944/full; https://doaj.org/toc/1664-3224
DOI: 10.3389/fimmu.2022.1056944
Access URL: https://doaj.org/article/e8f7a3ec71ec47e7acc6813331864085
Accession Number: edsdoj.8f7a3ec71ec47e7acc6813331864085
Database: Directory of Open Access Journals
More Details
ISSN:16643224
DOI:10.3389/fimmu.2022.1056944
Published in:Frontiers in Immunology
Language:English