Bibliographic Details
| Title: |
Quality of life in patients with primary biliary cholangitis: A cross-geographical comparison |
| Authors: |
Lorenzo Montali, Andrea Gragnano, Massimo Miglioretti, Alessandra Frigerio, Luca Vecchio, Alessio Gerussi, Laura Cristoferi, Vincenzo Ronca, Daphne D’Amato, Sarah Elizabeth O’Donnell, Clara Mancuso, Martina Lucà, Minami Yagi, Anna Reig, Laura Jopson, Sesé Pilar, Dave Jones, Albert Pares, George Mells, Atsushi Tanaka, Marco Carbone, Pietro Invernizzi |
| Source: |
Journal of Translational Autoimmunity, Vol 4, Iss , Pp 100081- (2021) |
| Publisher Information: |
Elsevier, 2021. |
| Publication Year: |
2021 |
| Collection: |
LCC:Immunologic diseases. Allergy |
| Subject Terms: |
Autoimmunity, Liver, Cholestasis, Fatigue, Immunologic diseases. Allergy, RC581-607 |
| More Details: |
Background & aims: Several symptoms impair the quality of life (QoL) of patients with primary biliary cholangitis (PBC). They are reported to vary significantly in different countries. Aim of our study was to explore whether there is a geographical clustering that accounts for symptoms in PBC. Methods: Data was analysed from four cohorts of PBC patients from the UK, Spain, Japan and Italy using the PBC-27 scale. Results: Overall, 569 patients from four cohorts were identified, including 515 females (90.5%) with a mean age of 61 years. The analysis provided evidence for strict factorial invariance of the scale, a robust indicator of its validity for cross-cultural research. The mean of the fatigue domain of British patients was significantly greater than that of the Japanese (p |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2589-9090 |
| Relation: |
http://www.sciencedirect.com/science/article/pii/S2589909021000010; https://doaj.org/toc/2589-9090 |
| DOI: |
10.1016/j.jtauto.2021.100081 |
| Access URL: |
https://doaj.org/article/8f5f7db2116f4ea4b9e21f5ab89adf1e |
| Accession Number: |
edsdoj.8f5f7db2116f4ea4b9e21f5ab89adf1e |
| Database: |
Directory of Open Access Journals |
