Clinical effectiveness of complete revascularization versus infarct-related artery-only percutaneous coronary revascularization for multivessel disease ST-segment elevation myocardial infarction

Bibliographic Details
Title: Clinical effectiveness of complete revascularization versus infarct-related artery-only percutaneous coronary revascularization for multivessel disease ST-segment elevation myocardial infarction
Authors: Joshua Chadwick Jayaraj
Source: Heart India, Vol 6, Iss 1, Pp 12-17 (2018)
Publisher Information: Wolters Kluwer Medknow Publications, 2018.
Publication Year: 2018
Collection: LCC:Diseases of the circulatory (Cardiovascular) system
Subject Terms: Complete revascularization, infarct-related artery, multivessel disease patients, primary percutaneous coronary angioplasty, ST-segment elevation patients, Diseases of the circulatory (Cardiovascular) system, RC666-701
More Details: Objectives: The purpose of this study was to evaluate the event-free survival from major adverse cardiac events for ST-segment elevation myocardial infarction (STEMI) patients with multivessel disease (MVD) as a function of whether they underwent infarct-related artery (IRA)- only percutaneous coronary intervention (PCI) or complete revascularization at index admission. Background: The optimal management of patients with STEMI and MVD while undergoing primary PCI (P-PCI) is uncertain. Methods and Results: STEMI patients with MVD undergoing P-PCI between April 1, 2012, and March 31, 2014, were subdivided into those who underwent complete revascularization during index admission (n = 150) and IRA-only revascularization (n = 156). Complete revascularization was performed at index admission of P-PCI. The primary endpoint was a composite of all-cause death, recurrent MI, heart failure (HF), and ischemia-driven revascularization within 24 months. Patient groups were differed at baseline by gender and prevalence of HF. The average door-to-balloon time was significantly higher in the complete revascularization group. The primary endpoint occurred in 11.0% of the complete revascularization group versus in 23% of the IRA-only revascularization group (hazard ratio: 0.51; 95% confidence interval: 0.34–0.93; P = 0.039). There was a significant reduction in death; a nonsignificant reduction in all primary endpoint components was seen. Conclusions: In patients presenting for P-PCI with MVD, complete revascularization at index admission significantly lowered the rate of the primary composite endpoint at 24 months compared with treating IRA-only.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2321-449X
Relation: http://www.heartindia.net/article.asp?issn=2321-449x;year=2018;volume=6;issue=1;spage=12;epage=17;aulast=Jayaraj; https://doaj.org/toc/2321-449X
DOI: 10.4103/heartindia.heartindia_32_17
Access URL: https://doaj.org/article/8f595be00cda420cacb1ad447df26db0
Accession Number: edsdoj.8f595be00cda420cacb1ad447df26db0
Database: Directory of Open Access Journals
More Details
ISSN:2321449X
DOI:10.4103/heartindia.heartindia_32_17
Published in:Heart India
Language:English