Impact of deceased-donor characteristics on early graft function: outcome of kidney donor pairs accepted for transplantation

Bibliographic Details
Title: Impact of deceased-donor characteristics on early graft function: outcome of kidney donor pairs accepted for transplantation
Authors: Christoph F. Mahler, Felix Friedl, Christian Nusshag, Claudius Speer, Louise Benning, Daniel Göth, Matthias Schaier, Claudia Sommerer, Markus Mieth, Arianeb Mehrabi, Lutz Renders, Uwe Heemann, Markus Krautter, Vedat Schwenger, Fabian Echterdiek, Martin Zeier, Christian Morath, Florian Kälble
Source: Frontiers in Immunology, Vol 15 (2024)
Publisher Information: Frontiers Media S.A., 2024.
Publication Year: 2024
Collection: LCC:Immunologic diseases. Allergy
Subject Terms: immunology, transplantation - kidney, transplantation, deceased donation, scores, Immunologic diseases. Allergy, RC581-607
More Details: IntroductionThe impact of deceased donor characteristics on kidney transplant outcomes is controversial. Correspondingly, the predictive performance of deceased donor scores remains moderate, and many transplant centers lack validated criteria for graft acceptance decisions. To better dissect donor-related risk from recipient and periprocedural variables, we analyzed outcomes of kidney donor pairs transplanted in different individuals.MethodsThis study explored (a)symmetry of early outcomes of 328 cadaveric kidney transplant recipients from 164 donor pairs transplanted at three Eurotransplant centers. The primary discriminatory factor was (a)symmetry of partner graft function, defined as early graft loss or impaired graft function [estimated glomerular filtration rate (eGFR)
Document Type: article
File Description: electronic resource
Language: English
ISSN: 1664-3224
Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2024.1303746/full; https://doaj.org/toc/1664-3224
DOI: 10.3389/fimmu.2024.1303746
Access URL: https://doaj.org/article/8edf63bba72a4c9ebd7ec4d076380905
Accession Number: edsdoj.8edf63bba72a4c9ebd7ec4d076380905
Database: Directory of Open Access Journals
More Details
ISSN:16643224
DOI:10.3389/fimmu.2024.1303746
Published in:Frontiers in Immunology
Language:English