Bibliographic Details
| Title: |
Establishment and validation of the cut-off values of estimated glomerular filtration rate and urinary albumin-to-creatinine ratio for diabetic kidney disease: A multi-center, prospective cohort study |
| Authors: |
Zhongai Gao, Yanjuan Zhu, Xiaoyue Sun, Hong Zhu, Wenhui Jiang, Mengdi Sun, Jingyu Wang, Le Liu, Hui Zheng, Yongzhang Qin, Shuang Zhang, Yanhui Yang, Jie Xu, Juhong Yang, Chunyan Shan, Baocheng Chang |
| Source: |
Frontiers in Endocrinology, Vol 13 (2022) |
| Publisher Information: |
Frontiers Media S.A., 2022. |
| Publication Year: |
2022 |
| Collection: |
LCC:Diseases of the endocrine glands. Clinical endocrinology |
| Subject Terms: |
diabetic kidney disease, estimated glomerular filtration rate, microalbuminuria, cardiovascular disease, diabetic metabolism, Diseases of the endocrine glands. Clinical endocrinology, RC648-665 |
| More Details: |
ObjectiveWe aimed to study the cut-off values of estimated glomerular filtration rate (eGFR) and the urinary albumin creatinine ratio (UACR) in the normal range for diabetic kidney disease (DKD).MethodsIn this study, we conducted a retrospective, observational cohort study included 374 type 2 diabetic patients who had baseline eGFR ≥60 mL/min/1.73 m2 and UACR 0.05). The discrimination of eGFR at the cut-off value of 84.80 mL/min/1.73 m2 or UACR at 15.5mg/g with the largest Youden’s index was further confirmed in the validation cohort. The decrease rate of eGFR was faster in patients with UACR ≥15.5mg/g (P |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
1664-2392 |
| Relation: |
https://www.frontiersin.org/articles/10.3389/fendo.2022.1064665/full; https://doaj.org/toc/1664-2392 |
| DOI: |
10.3389/fendo.2022.1064665 |
| Access URL: |
https://doaj.org/article/8e8567839e5b419a9556fcec2496ba76 |
| Accession Number: |
edsdoj.8e8567839e5b419a9556fcec2496ba76 |
| Database: |
Directory of Open Access Journals |
