Bibliographic Details
| Title: |
Analysis of the Development Trajectory of Health-related Quality of Life in Middle-aged and Elderly Patients with Cardiometabolic Diseases and the Influencing Factors |
| Authors: |
FAN Jianing, CHEN Jieting, WANG Ziqi, FAN Jinhe, JING Mingxia |
| Source: |
Zhongguo quanke yixue, Vol 28, Iss 08, Pp 923-932 (2025) |
| Publisher Information: |
Chinese General Practice Publishing House Co., Ltd, 2025. |
| Publication Year: |
2025 |
| Collection: |
LCC:Medicine |
| Subject Terms: |
health-related quality of life, cardiometabolic diseases, european quality of life 5-dimension 5-level version, middle-aged and elderly, growth mixture model, root cause analysis, shapley value method, Medicine |
| More Details: |
Background As the aging of the population, the burden of chronic diseases in China has increased significantly. The majority of chronic disease patients suffer from cardiometabolic diseases (CMD) like hypertension and diabetes. The health-related quality of life (HRQoL) is a subjective evaluation index that reflects both the physical health level and mental health of patients with chronic diseases. Existing research on HRQoL in patients with CMD primarily focuses on influencing factors and the assessment of their current status. Compared to the research on the static status of HRQoL, research on its dynamic trends over time, however, remains somewhat limited. Objective To analyze the development trajectory of HRQoL in middle-aged and elderly patients with CMD and influencing factors, as well as to explore the contribution of each influencing factor, thus providing a scientific basis for improving HRQoL in patients with CMD. Methods Using time-series data from field surveys, a baseline survey in 2016 (T0) was conducted using a typical sampling in eligible patients with primary hypertension or type 2 diabetes mellitus (T2DM) from 3 urban communities and 2 rural communities in a certain division of the Xinjiang Production and Construction Corps. Four follow-up surveys were conducted in 2017 (T1), 2018 (T2), 2019 (T3), and 2021 (T4). A total of 1 599 subjects were surveyed in the baseline period, and 565 subjects completed the follow-up visits. Of them, 389 had hypertension, and 176 had T2DM. After excluding samples with missing data like HRQoL and demographic characteristics, data from 563 subjects were included in the analysis. A self-designed questionnaire was used for the survey, composing of five parts of personal basic information, social and psychological status, lifestyle, disease status, and health service utilization. The HRQoL of patients was measured using the European Quality of Life 5-Dimension 5-Level version (EQ-5D-5L). The heterogeneous HRQoL development trajectories were explored using a growth mixture model, and the influencing factors and evaluation of the development trajectories were analyzed using a logistic regression model and Shapley value decomposition, respectively. Results Three distinct types of heterogeneous development trajectories were identified, including a 452 (80.28%) cases in the significant growth group, 81 (14.39%) cases in the moderate decline group, and 30 (5.33%) cases in the significant attenuation group. Multivariate Logistic regressions analysis indicated that, patients who do not engage in physical exercise, possess impaired self-care abilities, experience deteriorating health conditions, have non-urban employee medical insurance, and express dissatisfaction with the outpatient chronic disease policy were more likely to enter the moderate decline group (P |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
Chinese |
| ISSN: |
1007-9572 |
| Relation: |
https://www.chinagp.net/fileup/1007-9572/PDF/2024-050315.pdf; https://doaj.org/toc/1007-9572 |
| DOI: |
10.12114/j.issn.1007-9572.2024.0364 |
| Access URL: |
https://doaj.org/article/8e39e9828b104ca78883d5dbf51011f7 |
| Accession Number: |
edsdoj.8e39e9828b104ca78883d5dbf51011f7 |
| Database: |
Directory of Open Access Journals |
