Bibliographic Details
| Title: |
Desmoid-type fibromatosis of the breast: a case report and literature review |
| Authors: |
Zijun Zhao, Qingyao Shang, Chenxuan Yang, Jiaxiang Liu, Shanqing Liu, Xiaoqian Li, Xiyu Kang, Jiaxian Yue, Xin Wang, Xiang Wang |
| Source: |
Frontiers in Oncology, Vol 15 (2025) |
| Publisher Information: |
Frontiers Media S.A., 2025. |
| Publication Year: |
2025 |
| Collection: |
LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens |
| Subject Terms: |
desmoid-type fibromatosis, breast, case report, pathology, treatment, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282 |
| More Details: |
Breast desmoid-type fibromatosis (BDF) is a rare tumor predominated by mesenchymal cells. It has a high recurrence rate, although distal metastasis is uncommon. It resembles breast cancer clinically, and histological pathology is the only approach to a confirmed diagnosis. Comprehensive and individualized treatments were recommended for BDF patients. Here, we presented a case of BDF secondary to primary breast carcinoma in our center. A 47-year-old female complained of a large mass in her left breast for 2.5 months. She has a past history of left breast carcinoma with a failure of surgical and systemic intervention. Despite an active re-operation, she still suffered from disease progression with a bad prognosis. After our report, the clinicopathological traits, differential diagnosis of BDF and current recommendation of management were discussed. This case report aimed to make a clear recognition of this rare and aggressive disease and elaborate up-to-date treatment recommendations. More effective drugs and larger sample clinical studies are encouraged for better management of refractory and progressive BDF. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2234-943X |
| Relation: |
https://www.frontiersin.org/articles/10.3389/fonc.2025.1482024/full; https://doaj.org/toc/2234-943X |
| DOI: |
10.3389/fonc.2025.1482024 |
| Access URL: |
https://doaj.org/article/a8e1f27eeaf54401b1b473e232cff2f5 |
| Accession Number: |
edsdoj.8e1f27eeaf54401b1b473e232cff2f5 |
| Database: |
Directory of Open Access Journals |
