Erythema in local and trunk skin caused by intramuscular injection of vitamin K1: A case report and literature review

Bibliographic Details
Title: Erythema in local and trunk skin caused by intramuscular injection of vitamin K1: A case report and literature review
Authors: Cai-Xia Hu, Yu Cui, Hui Liu, Xiao-Mei Han, Shao-Qian Jiang, Lu Zhao, Wen-Qing Wang
Source: European Journal of Inflammation, Vol 19 (2021)
Publisher Information: SAGE Publishing, 2021.
Publication Year: 2021
Collection: LCC:Medicine
Subject Terms: Medicine
More Details: A 52-year-old woman presented with erythema, papules, pain, and itching on the buttocks and trunk that had persisted for 1 week. Twenty-two days before admission, the patient received three intramuscular injections of vitamin K1 in the gluteal muscles. Two weeks after the last intramuscular injection edematous hard erythema developed bilaterally on the gluteal muscles, accompanied by itching, pain, and a burning sensation. Afterward, the erythema and papules gradually spread to the trunk, with notable itching. Dermatological examination revealed a large area of well-defined edematous hard erythema, and blisters around the injection sites on both hips. The skin temperature was high, with mild tenderness. Dense distributions of edematous erythema and papules were observed on the trunk, some of which were fused into pieces. The patient received a diagnosis of a skin reaction induced by intramuscular injections of vitamin K1. Therefore, she was administered glycyrrhizin, calcium, vitamin C, antihistamines, topical polysulfonic mucopolysaccharide cream, and glucocorticoid cream, and the lesions subsided after 2 weeks.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2058-7392
20587392
Relation: https://doaj.org/toc/2058-7392
DOI: 10.1177/20587392211066423
Access URL: https://doaj.org/article/8df4913b0bca4a2d977c3cf1a2870a49
Accession Number: edsdoj.8df4913b0bca4a2d977c3cf1a2870a49
Database: Directory of Open Access Journals
Full text is not displayed to guests.
More Details
ISSN:20587392
DOI:10.1177/20587392211066423
Published in:European Journal of Inflammation
Language:English