Influence of Brainstem’s Area A5 on Sympathetic Outflow and Cardiorespiratory Dynamics

Bibliographic Details
Title: Influence of Brainstem’s Area A5 on Sympathetic Outflow and Cardiorespiratory Dynamics
Authors: Isabel Rocha, Marta González-García, Laura Carrillo-Franco, Marc Stefan Dawid-Milner, Manuel Victor López-González
Source: Biology, Vol 13, Iss 3, p 161 (2024)
Publisher Information: MDPI AG, 2024.
Publication Year: 2024
Collection: LCC:Biology (General)
Subject Terms: area A5, sympathetic nervous system, cardiovascular regulation, brainstem neurochemistry, autonomic response, Biology (General), QH301-705.5
More Details: Area A5 is a noradrenergic cell group in the brain stem characterised by its important role in triggering sympathetic activity, exerting a profound influence on the sympathetic outflow, which is instrumental in the modulation of cardiovascular functions, stress responses and various other physiological processes that are crucial for adaptation and survival mechanisms. Understanding the role of area A5, therefore, not only provides insights into the basic functioning of the sympathetic nervous system but also sheds light on the neuronal basis of a number of autonomic responses. In this review, we look deeper into the specifics of area A5, exploring its anatomical connections, its neurochemical properties and the mechanisms by which it influences sympathetic nervous system activity and cardiorespiratory regulation and, thus, contributes to the overall dynamics of the autonomic function in regulating body homeostasis.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2079-7737
Relation: https://www.mdpi.com/2079-7737/13/3/161; https://doaj.org/toc/2079-7737
DOI: 10.3390/biology13030161
Access URL: https://doaj.org/article/8da5e6186d5044a8a6c13a8543d4bda5
Accession Number: edsdoj.8da5e6186d5044a8a6c13a8543d4bda5
Database: Directory of Open Access Journals
More Details
ISSN:20797737
DOI:10.3390/biology13030161
Published in:Biology
Language:English