Academic Journal
Research progress on long non-coding RNAs for spinal cord injury
| Title: | Research progress on long non-coding RNAs for spinal cord injury |
|---|---|
| Authors: | Musen Zhong, Guangya Fan, Zhongcheng An, Chen Chen, Liqiang Dong |
| Source: | Journal of Orthopaedic Surgery and Research, Vol 18, Iss 1, Pp 1-8 (2023) |
| Publisher Information: | BMC, 2023. |
| Publication Year: | 2023 |
| Collection: | LCC:Orthopedic surgery LCC:Diseases of the musculoskeletal system |
| Subject Terms: | Long non-coding RNA, Spinal cord injury, Mechanism of action, Signaling pathway, Orthopedic surgery, RD701-811, Diseases of the musculoskeletal system, RC925-935 |
| More Details: | Abstract Spinal cord injury is a complex central nervous system disease with an unsatisfactory prognosis, often accompanied by multiple pathological processes. However, the underlying mechanisms of action of this disease are unclear, and there are no suitable targeted therapeutic options. Long non-coding RNA mediates a variety of neurological diseases and regulates various biological processes, including apoptosis and autophagy, inflammatory response, microenvironment, and oxidative stress. It is known that long non-coding RNAs have significant differences in gene expression in spinal cord injury. To further understand the mechanism of long non-coding RNA action in spinal cord injury and develop preventive and therapeutic strategies regarding spinal cord injury, this review outlines the current status of research between long non-coding RNAs and spinal cord injury and potential long non-coding RNAs targeting spinal cord injury. |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English |
| ISSN: | 1749-799X |
| Relation: | https://doaj.org/toc/1749-799X |
| DOI: | 10.1186/s13018-023-03989-x |
| Access URL: | https://doaj.org/article/8d86a8cd9f02408cb0e63d1687272537 |
| Accession Number: | edsdoj.8d86a8cd9f02408cb0e63d1687272537 |
| Database: | Directory of Open Access Journals |
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| ISSN: | 1749799X |
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| DOI: | 10.1186/s13018-023-03989-x |
| Published in: | Journal of Orthopaedic Surgery and Research |
| Language: | English |