Hemorrhagic cystitis: A successful outcome for a challenging complication in stem cell transplant

Bibliographic Details
Title:	Hemorrhagic cystitis: A successful outcome for a challenging complication in stem cell transplant
Authors:	Sergio Pinzón Mariño, Samira Bakali Badesa, María Jesús Viso Soriano, Isabel Izquierdo Garcia
Source:	Hematology Reports, Vol 13, Iss 1 (2021)
Publisher Information:	MDPI AG, 2021.
Publication Year:	2021
Collection:	LCC:Diseases of the blood and blood-forming organs
Subject Terms:	BK virus, Cidofovir, Hematopoietic stem cell transplantation, Virus-associated hemorrhagic cystitis, Diseases of the blood and blood-forming organs, RC633-647.5
More Details:	Hemorrhagic cystitis (HC) secondary to BK polyomavirus (BKPyV) is a frequent complication related to allogenic stem cell transplantation. With an important morbidity and mortality, this disease doesn’t have a stablished standard treatment or prophylaxis strategies. At this moment, the supportive therapies approved to treat included hyperhydration, forced diuresis and transfusion support. Cidofovir is a nucleotide analog of deoxycytidine monophosphate against DNA viruses and it has been described for the treatment of BKPyV-HC, but at this moment, is not a front-line therapy. We report a successful case after the use of Cidofovir without Probenecid. No adverse effect was developed under the treatment, and after 4 weeks of treatment, the patient achieved an excellent response.
Document Type:	article
File Description:	electronic resource
Language:	English
ISSN:	2038-8322 2038-8330
Relation:	https://pagepress.org/journals/index.php/hr/article/view/8574; https://doaj.org/toc/2038-8322; https://doaj.org/toc/2038-8330
DOI:	10.4081/hr.2021.8574
Access URL:	https://doaj.org/article/dcac8c78fbf7413ea127bb09d93af315
Accession Number:	edsdoj.8c78fbf7413ea127bb09d93af315
Database:	Directory of Open Access Journals

More Details
ISSN:	20388322 20388330
DOI:	10.4081/hr.2021.8574
Published in:	Hematology Reports
Language:	English