Bibliographic Details
Title: |
COVID-19 Infection Risk Following Elective Arthroplasty and Surgical Complications in COVID-19-vaccinated Patients: A Multicenter Comparative Cohort Study |
Authors: |
Seyed Peyman Mirghaderi, MD, Maryam Salimi, MD, Alireza Moharrami, MD, Reza Hosseini-Dolama, MD, Seyed Reza Mirghaderi, MD, Milad Ghaderi, Mehdi Motififard, MD, Seyed Mohammad Javad Mortazavi, MD |
Source: |
Arthroplasty Today, Vol 18, Iss , Pp 76-83 (2022) |
Publisher Information: |
Elsevier, 2022. |
Publication Year: |
2022 |
Collection: |
LCC:Orthopedic surgery |
Subject Terms: |
Arthroplasty, COVID-19, Elective, Vaccines, Venous thrombosis, Orthopedic surgery, RD701-811 |
More Details: |
Background: We aimed to determine symptomatic Coronavirus disease 2019 (COVID-19) rates within 1 month of elective arthroplasty for vaccinated individuals and to determine whether vaccination guarantees protection against COVID-19 after arthroplasty (primary outcome). In addition, the 90-day surgical complications were compared to those of an unvaccinated group (secondary outcome). Methods: A prospective cohort study was conducted on elective joint arthroplasty patients at 3 tertiary hospitals in 2 major cities (Tehran and Isfahan) in our country (Iran). The outcomes of the COVID-19-vaccinated group were assessed between October 2021 and March 2022. Ninety-day surgical complications were compared with a historical cohort of unvaccinated patients treated earlier in the pandemic (April 2020-March 2021). Results: The study included 1717 consecutive patients: 962 vaccinated and 755 unvaccinated. In the vaccinated group, 38 patients (3.9%) contracted COVID-19, 4 (10.5%) were hospitalized again, and none required intensive care unit admission. The multivariate logistic regression analysis revealed that COVID-19-positive cases are more likely to be female (odds ratio [OR] = 12.5), to have visitors to their home (OR = 4.7), and to stay longer in the hospital (OR = 1.2) than COVID-19-negative cases. Compared to unvaccinated patients, the postoperative COVID-19 rate was not significantly different (3.9% vs 2.4%, P = .07). The incidence of surgical complications was similar between the 2 groups (P > .05). Conclusions: The vaccination does not provide a guarantee that a patient will not contract COVID-19 following their arthroplasty surgery, especially in a region with a high rate of COVID-19. We believe reasonable perioperative COVID-19 precautions may be warranted even in vaccinated patients. |
Document Type: |
article |
File Description: |
electronic resource |
Language: |
English |
ISSN: |
2352-3441 |
Relation: |
http://www.sciencedirect.com/science/article/pii/S2352344122002138; https://doaj.org/toc/2352-3441 |
DOI: |
10.1016/j.artd.2022.09.005 |
Access URL: |
https://doaj.org/article/8c190a9ae35d484e810c35fb858edc07 |
Accession Number: |
edsdoj.8c190a9ae35d484e810c35fb858edc07 |
Database: |
Directory of Open Access Journals |