Epidemiological and genetic investigation of a cluster of cases of severe fever with thrombocytopenia syndrome bunyavirus

Bibliographic Details
Title: Epidemiological and genetic investigation of a cluster of cases of severe fever with thrombocytopenia syndrome bunyavirus
Authors: Lingling Mao, Baocheng Deng, Yuhong Liang, Yun Liu, Zijiang Wang, Jie Zhang, Wei Wu, Lei Yu, Wenqing Yao
Source: BMC Infectious Diseases, Vol 20, Iss 1, Pp 1-6 (2020)
Publisher Information: BMC, 2020.
Publication Year: 2020
Collection: LCC:Infectious and parasitic diseases
Subject Terms: SFTS, Cluster outbreak, Molecular epidemiology, SFTSV, Infectious and parasitic diseases, RC109-216
More Details: Abstract Background To analyze and discuss the transmission route of a cluster of cases of severe fever with thrombocytopenia syndrome bunyavirus (SFTSV). Method We performed an epidemiological investigation and a genetic analysis of patients with severe fever with thrombocytopenia syndrome (SFTS) caused by SFTSV, their close contacts and the surrounding population. Results We found that all patients had contact with the blood of the first patient. The comparison of gene sequences in the three isolated SFTSV strains showed that the strains were closely related. Six close contacts and nine individuals in the surrounding population were positive for SFTSV IgM antibody. Conclusion We suspect that the cluster outbreak was transmitted via blood and that the natural reservoir host of SFTSV exists in the patients’ environment.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 1471-2334
Relation: http://link.springer.com/article/10.1186/s12879-020-05072-w; https://doaj.org/toc/1471-2334
DOI: 10.1186/s12879-020-05072-w
Access URL: https://doaj.org/article/d8befd3c27ce4dc2b76cd6fa9869f802
Accession Number: edsdoj.8befd3c27ce4dc2b76cd6fa9869f802
Database: Directory of Open Access Journals
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More Details
ISSN:14712334
DOI:10.1186/s12879-020-05072-w
Published in:BMC Infectious Diseases
Language:English