Bibliographic Details
| Title: |
Comparisons of open surgical repair, thoracic endovascular aortic repair, and optimal medical therapy for acute and subacute type B aortic dissection: a systematic review and meta-analysis |
| Authors: |
Jianping Liu, Xiaohong Chen, Juan Xia, Long Tang, Yongheng Zhang, Lin Cao, Yong Zheng |
| Source: |
BMC Cardiovascular Disorders, Vol 25, Iss 1, Pp 1-16 (2025) |
| Publisher Information: |
BMC, 2025. |
| Publication Year: |
2025 |
| Collection: |
LCC:Diseases of the circulatory (Cardiovascular) system |
| Subject Terms: |
Open surgical repair, Thoracic endovascular aortic repair, Optimal medical therapy, Type B aortic dissection, Systematic review, Network meta-analysis, Diseases of the circulatory (Cardiovascular) system, RC666-701 |
| More Details: |
Abstract Background Various treatments have been employed in managing type B aortic dissection (TBAD), encompassing open surgical repair (OSR), thoracic endovascular aortic repair (TEVAR), and optimal medical therapy (OMT). Nonetheless, the determination of the most efficacious treatment protocol remains a subject of debate. We aim to compare the treatments in patients with acute and subacute TBAD using a meta-analytic approach. Methods A systematic search was conducted across databases including PubMed, EmBase, and the Cochrane Library for relevant studies published from their inception up to September 2024. Studies comparing OSR, TEVAR, and OMT for TBAD through controlled or direct comparative designs were incorporated. Pairwise comparison meta-analyses were performed employing odds ratios (OR) alongside 95% confidence intervals (CIs) to quantify intervention effects by using the random-effects model. Results Thirty-one studies involving 34,681 patients with TBAD were included in the final meta-analysis. We noted OSR were associated with an increased risk of in-hospital mortality (OR: 2.41; 95%CI: 1.67–3.49; P |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
1471-2261 |
| Relation: |
https://doaj.org/toc/1471-2261 |
| DOI: |
10.1186/s12872-025-04478-1 |
| Access URL: |
https://doaj.org/article/8bafdd965ac54dae8aafd3834f79b16e |
| Accession Number: |
edsdoj.8bafdd965ac54dae8aafd3834f79b16e |
| Database: |
Directory of Open Access Journals |
