Bibliographic Details
| Title: |
A post-transcriptional program coordinated by CSDE1 prevents intrinsic neural differentiation of human embryonic stem cells |
| Authors: |
Hyun Ju Lee, Deniz Bartsch, Cally Xiao, Santiago Guerrero, Gaurav Ahuja, Christina Schindler, James J. Moresco, John R. Yates, Fátima Gebauer, Hisham Bazzi, Christoph Dieterich, Leo Kurian, David Vilchez |
| Source: |
Nature Communications, Vol 8, Iss 1, Pp 1-19 (2017) |
| Publisher Information: |
Nature Portfolio, 2017. |
| Publication Year: |
2017 |
| Collection: |
LCC:Science |
| Subject Terms: |
Science |
| More Details: |
Unlike transcriptional regulation of hESC identity, little is known post-transcriptionally. Here, the authors show that the RNA binding protein CSDE1 regulates core components of hESC identity, neurectoderm commitment and neurogenesis to maintain pluripotency and prevent neural differentiation. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2041-1723 |
| Relation: |
https://doaj.org/toc/2041-1723 |
| DOI: |
10.1038/s41467-017-01744-5 |
| Access URL: |
https://doaj.org/article/8b637ecfb83f4e0ea34de34086340b09 |
| Accession Number: |
edsdoj.8b637ecfb83f4e0ea34de34086340b09 |
| Database: |
Directory of Open Access Journals |
