Bibliographic Details
Title: |
Analysis of DNA methylation associates the cystine–glutamate antiporter SLC7A11 with risk of Parkinson’s disease |
Authors: |
Costanza L. Vallerga, Futao Zhang, Javed Fowdar, Allan F. McRae, Ting Qi, Marta F. Nabais, Qian Zhang, Irfahan Kassam, Anjali K. Henders, Leanne Wallace, Grant Montgomery, Yu-Hsuan Chuang, Steve Horvath, Beate Ritz, Glenda Halliday, Ian Hickie, John B. Kwok, John Pearson, Toni Pitcher, Martin Kennedy, Steven R. Bentley, Peter A. Silburn, Jian Yang, Naomi R. Wray, Simon J. G. Lewis, Tim Anderson, John Dalrymple-Alford, George D. Mellick, Peter M. Visscher, Jacob Gratten |
Source: |
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020) |
Publisher Information: |
Nature Portfolio, 2020. |
Publication Year: |
2020 |
Collection: |
LCC:Science |
Subject Terms: |
Science |
More Details: |
Parkinson’s disease (PD) is a common neurodegenerative disorder with a complex etiology involving genetics and the environment. Here, Vallerga et al. identify two CpG probes associated with PD in a blood cell type-corrected epigenome-wide meta-analysis, implicating the SLC7A11 gene as a plausible biological target. |
Document Type: |
article |
File Description: |
electronic resource |
Language: |
English |
ISSN: |
2041-1723 |
Relation: |
https://doaj.org/toc/2041-1723 |
DOI: |
10.1038/s41467-020-15065-7 |
Access URL: |
https://doaj.org/article/8ab912eda75443699d2e15309d47801d |
Accession Number: |
edsdoj.8ab912eda75443699d2e15309d47801d |
Database: |
Directory of Open Access Journals |