Association of malnutrition status with 30-day mortality in patients with sepsis using objective nutritional indices: a multicenter retrospective study in South Korea
| Title: | Association of malnutrition status with 30-day mortality in patients with sepsis using objective nutritional indices: a multicenter retrospective study in South Korea |
|---|---|
| Authors: | Moon Seong Baek, Young Suk Kwon, Sang Soo Kang, Daechul Shim, Youngsang Yoon, Jong Ho Kim |
| Source: | Acute and Critical Care, Vol 39, Iss 1, Pp 127-137 (2024) |
| Publisher Information: | Korean Society of Critical Care Medicine, 2024. |
| Publication Year: | 2024 |
| Collection: | LCC:Medical emergencies. Critical care. Intensive care. First aid |
| Subject Terms: | malnutrition, mechanical ventilation, mortality, nutritional status, sepsis, Medical emergencies. Critical care. Intensive care. First aid, RC86-88.9 |
| More Details: | Background The Controlling Nutritional Status (CONUT) score and the prognostic nutritional index (PNI) have emerged as important nutritional indices because they provide an objective assessment based on data. We aimed to investigate how these nutritional indices relate to outcomes in patients with sepsis. Methods Data were collected retrospectively at five hospitals for patients aged ≥18 years receiving treatment for sepsis between January 1, 2017, and December 31, 2021. Serum albumin and total cholesterol concentrations, and peripheral lymphocytes were used to calculate the CONUT score and PNI. To identify predictors correlated with 30-day mortality, analyses were conducted using univariate and multivariate Cox proportional hazards models. Results The 30-day mortality rate among 9,763 patients was 15.8% (n=1,546). The median CONUT score was 5 (interquartile range [IQR], 3–7) and the median PNI score was 39.6 (IQR, 33.8–46.4). Higher 30-day mortality rates were associated with individuals with moderate (CONUT score: 5–8; PNI: 35–38) or severe (CONUT: 9–12; PNI: 38). With CONUT scores, the hazard ratio (HR) associated with moderate malnutrition was 1.52 (95% confidence interval [CI], 1.24–1.87; P |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English |
| ISSN: | 2586-6052 2586-6060 |
| Relation: | http://www.accjournal.org/upload/pdf/acc-2023-01613.pdf; https://doaj.org/toc/2586-6052; https://doaj.org/toc/2586-6060 |
| DOI: | 10.4266/acc.2023.01613 |
| Access URL: | https://doaj.org/article/8a78f3a1c3fd4f61966e6480b0c6c46a |
| Accession Number: | edsdoj.8a78f3a1c3fd4f61966e6480b0c6c46a |
| Database: | Directory of Open Access Journals |
| ISSN: | 25866052 25866060 |
|---|---|
| DOI: | 10.4266/acc.2023.01613 |
| Published in: | Acute and Critical Care |
| Language: | English |