Bibliographic Details
| Title: |
An Efficient Synthesis of Enantiopure (R)-heteroarylpyrimidine Analogs |
| Authors: |
Guo-Ming Zhao, Zhi-Bing Zheng, Dong-Mei Zhao, Xiao-Kui Wang, Guang-Qiang Xia, Xiu-Yan Yang, Song Li |
| Source: |
Molecules, Vol 18, Iss 9, Pp 11144-11152 (2013) |
| Publisher Information: |
MDPI AG, 2013. |
| Publication Year: |
2013 |
| Collection: |
LCC:Organic chemistry |
| Subject Terms: |
anti-HBV, enantiopure, (R)-heteroarylpyrimidines, chiral separation, diastereomer, Organic chemistry, QD241-441 |
| More Details: |
An efficient synthesis of enantiopure (R)-heteroarylpyrimidine analogs is described here, which involves introduction of a chiral group, formation and separation of diasteroisomers and final transformation of an amide to an ester. The absolute configuration of the enantiopure HAPs is confirmed by X-ray analysis of their intermediates. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
1420-3049 |
| Relation: |
http://www.mdpi.com/1420-3049/18/9/11144; https://doaj.org/toc/1420-3049 |
| DOI: |
10.3390/molecules180911144 |
| Access URL: |
https://doaj.org/article/8a33f4e2d43e4ad7aa5696328068f126 |
| Accession Number: |
edsdoj.8a33f4e2d43e4ad7aa5696328068f126 |
| Database: |
Directory of Open Access Journals |
