Bibliographic Details
| Title: |
Primary lateral sclerosis plus parkinsonism: a case report |
| Authors: |
Abhaya Moturu, Wade Welch |
| Source: |
BMC Neurology, Vol 23, Iss 1, Pp 1-7 (2023) |
| Publisher Information: |
BMC, 2023. |
| Publication Year: |
2023 |
| Collection: |
LCC:Neurology. Diseases of the nervous system |
| Subject Terms: |
Primary lateral sclerosis, Parkinsonism, Upper motor neuron symptoms, Pyramidal features, Extrapyramidal features, Neurology. Diseases of the nervous system, RC346-429 |
| More Details: |
Abstract Background The standard of diagnosing primary lateral sclerosis, the Pringle criteria, requires three years of purely upper motor neuron symptom presentation before confirming diagnosis. This classic standard has been questioned on occasion due to its restrictive range of both time period and symptomatic exhibition. Case presentation This case report will review a 57-year-old Caucasian female who presented with pyramidal and extrapyramidal features suggestive of the exceedingly rare disease primary lateral sclerosis plus parkinsonism. We will describe the mixture of upper motor neuron signs and striking parkinsonian symptoms experienced by the patient, as well as the full diagnostic workup leading to her preliminary diagnosis. The details of this case will then be utilized to explore the diagnostic criteria of primary lateral sclerosis, as well as to work through the differential of conditions resembling Parkinson’s disease. Conclusions The current criteria to diagnose primary lateral sclerosis may be excluding patients with the disease and is an ongoing area of investigation. A thorough differential including other neurodegenerative conditions is necessary to consider and requires long-term follow-up. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
1471-2377 |
| Relation: |
https://doaj.org/toc/1471-2377 |
| DOI: |
10.1186/s12883-023-03360-x |
| Access URL: |
https://doaj.org/article/d89f4c3671f74ce6a6ff5bba88d97393 |
| Accession Number: |
edsdoj.89f4c3671f74ce6a6ff5bba88d97393 |
| Database: |
Directory of Open Access Journals |
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