Bibliographic Details
| Title: |
Sex differences in heart mitochondria regulate diastolic dysfunction |
| Authors: |
Yang Cao, Laurent Vergnes, Yu-Chen Wang, Calvin Pan, Karthickeyan Chella Krishnan, Timothy M. Moore, Manuel Rosa-Garrido, Todd H. Kimball, Zhiqiang Zhou, Sarada Charugundla, Christoph D. Rau, Marcus M. Seldin, Jessica Wang, Yibin Wang, Thomas M. Vondriska, Karen Reue, Aldons J. Lusis |
| Source: |
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022) |
| Publisher Information: |
Nature Portfolio, 2022. |
| Publication Year: |
2022 |
| Collection: |
LCC:Science |
| Subject Terms: |
Science |
| More Details: |
In this paper, the authors show that sex differences in mitochondrial DNA levels and function in the heart contribute to sex biases in functions relevant to heart failure, identifying Acsl6 as a mitochondrial sex-biased regulator of diastolic function. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2041-1723 |
| Relation: |
https://doaj.org/toc/2041-1723 |
| DOI: |
10.1038/s41467-022-31544-5 |
| Access URL: |
https://doaj.org/article/89de6b77175046a88778990393d83932 |
| Accession Number: |
edsdoj.89de6b77175046a88778990393d83932 |
| Database: |
Directory of Open Access Journals |
