Bibliographic Details
| Title: |
Ocular perfusion pressure is not reduced in response to lower body negative pressure |
| Authors: |
Eric A. Hall, Richard S. Whittle, Ana Diaz-Artiles |
| Source: |
npj Microgravity, Vol 10, Iss 1, Pp 1-8 (2024) |
| Publisher Information: |
Nature Portfolio, 2024. |
| Publication Year: |
2024 |
| Collection: |
LCC:Biotechnology
LCC:Physiology |
| Subject Terms: |
Biotechnology, TP248.13-248.65, Physiology, QP1-981 |
| More Details: |
Abstract Lower body negative pressure (LBNP) has been proposed as a countermeasure to mitigate the cephalad fluid shift occurring during spaceflight, which may be associated with the development of Spaceflight Associated Neuro-ocular Syndrome (SANS). This study quantifies the effect of LBNP on intraocular pressure (IOP), mean arterial pressure at eye level (MAPeye), and ocular perfusion pressure (OPP). Twenty-four subjects (12 male, 12 female) were subjected to graded LBNP in 0° supine and 15° head-down tilt (HDT) postures from 0 mmHg to –50 mmHg in 10 mmHg increments. IOP decreased significantly with LBNP pressure in 0° supine (by 0.7 ± 0.09 mmHg per 10 mmHg LBNP pressure, p |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2373-8065 |
| Relation: |
https://doaj.org/toc/2373-8065 |
| DOI: |
10.1038/s41526-024-00404-5 |
| Access URL: |
https://doaj.org/article/897627107f994494a844dcf085058c35 |
| Accession Number: |
edsdoj.897627107f994494a844dcf085058c35 |
| Database: |
Directory of Open Access Journals |
