Liver resection for breast cancer-related liver metastases: a case report

Bibliographic Details
Title: Liver resection for breast cancer-related liver metastases: a case report
Authors: Eko Adhi Pangarsa, Erik Prabowo, Subiyakto, Wasisto Dwi Yudisaputro, Hermawan Istiadi, Jessica Novia Hadiyanto, Kevin Tandarto, Daniel Rizky, Budi Setiawan, Damai Santosa, Catharina Suharti
Source: Journal of Medical Case Reports, Vol 18, Iss 1, Pp 1-6 (2024)
Publisher Information: BMC, 2024.
Publication Year: 2024
Collection: LCC:Medicine
Subject Terms: Breast cancer, Liver metastasis, Hepatic resection, Systemic therapy, Multidisciplinary approach, Prognostic factors, Medicine
More Details: Abstract Introduction Breast cancer liver metastasis presents a significant challenge in clinical oncology, with limited treatment options and poor prognosis. This case series study explores the extended survival achieved in breast cancer patients with liver metastases through a combination of surgical and medical interventions. Case presentation We present three cases of Javanese female patients with breast cancer (51 years old, 42 years old, and 55 years old) with liver metastases who underwent hepatic resection followed by systemic therapy. The cases illustrate successful outcomes with disease-free survival ranging from 5 to 31 months post-surgery. Key prognostic factors associated with improved survival include prolonged interval between initial diagnosis and detection of liver metastasis, liver-limited disease, positive response to preoperative systemic therapy, and expression of estrogen and progesterone receptors in the metastatic lesions. Conclusion These findings underscore the potential efficacy of a multidisciplinary approach integrating local hepatectomy with systemic therapy in selected patients with breast cancer liver metastasis. Further research is warranted to identify optimal patient selection criteria and refine treatment strategies for improved outcomes.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 1752-1947
Relation: https://doaj.org/toc/1752-1947
DOI: 10.1186/s13256-024-05001-4
Access URL: https://doaj.org/article/88f3c734e4a8483c9639d2a0827027e4
Accession Number: edsdoj.88f3c734e4a8483c9639d2a0827027e4
Database: Directory of Open Access Journals
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More Details
ISSN:17521947
DOI:10.1186/s13256-024-05001-4
Published in:Journal of Medical Case Reports
Language:English