Bibliographic Details
Title: |
GPR180 is a component of TGFβ signalling that promotes thermogenic adipocyte function and mediates the metabolic effects of the adipocyte-secreted factor CTHRC1 |
Authors: |
Lucia Balazova, Miroslav Balaz, Carla Horvath, Áron Horváth, Caroline Moser, Zuzana Kovanicova, Adhideb Ghosh, Umesh Ghoshdastider, Vissarion Efthymiou, Elke Kiehlmann, Wenfei Sun, Hua Dong, Lianggong Ding, Ez-Zoubir Amri, Pirjo Nuutila, Kirsi A. Virtanen, Tarja Niemi, Barbara Ukropcova, Jozef Ukropec, Pawel Pelczar, Thorsten Lamla, Bradford Hamilton, Heike Neubauer, Christian Wolfrum |
Source: |
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021) |
Publisher Information: |
Nature Portfolio, 2021. |
Publication Year: |
2021 |
Collection: |
LCC:Science |
Subject Terms: |
Science |
More Details: |
Activation of thermogenic adipocytes is a strategy to combat metabolic diseases. Here the authors report that GPR180 is a component of TGFβ signalling that promotes thermogenic adipocyte function and mediates the metabolic effects of the adipocyte-secreted factor CTHRC1, and contributes to the regulation of glucose and energy metabolism. |
Document Type: |
article |
File Description: |
electronic resource |
Language: |
English |
ISSN: |
2041-1723 |
Relation: |
https://doaj.org/toc/2041-1723 |
DOI: |
10.1038/s41467-021-27442-x |
Access URL: |
https://doaj.org/article/88ee4530cad64964a1bb8fbac9b2b659 |
Accession Number: |
edsdoj.88ee4530cad64964a1bb8fbac9b2b659 |
Database: |
Directory of Open Access Journals |