Lymph Node and Bone Marrow Micro-Metastasis in Patients with Esophageal Cancer
| Title: | Lymph Node and Bone Marrow Micro-Metastasis in Patients with Esophageal Cancer |
|---|---|
| Authors: | Ali Esparham, Fatemeh Sadat Hashemi Javaheri, Sara Saffar Soflaei, Gordon A. Ferns, Majid Ghayour-Mobarhan, Maryam Saberi-Karimian, Reza Bagheri |
| Source: | Journal of Cardio-Thoracic Medicine, Vol 12, Iss 3, Pp 1361-1373 (2024) |
| Publisher Information: | Mashhad University of Medical Sciences, 2024. |
| Publication Year: | 2024 |
| Collection: | LCC:Diseases of the circulatory (Cardiovascular) system LCC:Diseases of the respiratory system |
| Subject Terms: | esophageal cancer, esophageal squamous cell carcinoma, esophageal adenocarcinoma, micro-metastasis, lymph node, bone marrow, Diseases of the circulatory (Cardiovascular) system, RC666-701, Diseases of the respiratory system, RC705-779 |
| More Details: | Esophageal cancer (EC) is the sixth most common cause of cancer-related mortality globally, due to the high frequency of early metastatic disease. In the past, the presence of metastasis was examined based on histological analysis using hematoxylin and eosin (HE) staining. A high percentage of patients experience recurrence after metastasectomy. Recurrence could be due to the presence of micro-metastasis (MM), which could be detected at sites such as lymph nodes or bone marrow using RT-PCR or immune-histochemical staining. Previous studies have reported inconsistent results with respect to the clinical significance of MM, its impact on survival, and how it is affected by chemotherapy. In this study, we reviewed the (1) clinical significance of MM, (2) methods of detection, (3) sites of occurrence, (4) the mechanism associated with MM, and (5) the role of chemotherapy and radiotherapy in patients with EC. |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English |
| ISSN: | 2345-2447 2322-5750 |
| Relation: | https://jctm.mums.ac.ir/article_24967_8b28132f1699475d5f07e1bcbcd3dbd6.pdf; https://doaj.org/toc/2345-2447; https://doaj.org/toc/2322-5750 |
| DOI: | 10.22038/jctm.2024.82376.1471 |
| Access URL: | https://doaj.org/article/884c9b172d084863a1ab58ab85fe7fa0 |
| Accession Number: | edsdoj.884c9b172d084863a1ab58ab85fe7fa0 |
| Database: | Directory of Open Access Journals |
| ISSN: | 23452447 23225750 |
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| DOI: | 10.22038/jctm.2024.82376.1471 |
| Published in: | Journal of Cardio-Thoracic Medicine |
| Language: | English |