Bibliographic Details
Title: |
Prevalence of asymptomatic Leishmania donovani infection and associated factors in Ethiopia: a systematic review and meta-analysis |
Authors: |
Habtamu Belay, Adugna Abera, Esayas Aklilu, Tesfahun Bishaw, Ayinalem Alemu, Geremew Tasew, Berhanu Erko |
Source: |
BMC Infectious Diseases, Vol 25, Iss 1, Pp 1-13 (2025) |
Publisher Information: |
BMC, 2025. |
Publication Year: |
2025 |
Collection: |
LCC:Infectious and parasitic diseases |
Subject Terms: |
Asymptomatic, Epidemiology, Visceral leishmaniasis, L. donovani, Pooled estimate, Risk factors, Infectious and parasitic diseases, RC109-216 |
More Details: |
Abstract Background Visceral leishmaniasis is endemic in Ethiopia and caused by Leishmania donovani. Although the disease manifests with significant clinical variability, a substantial number of individuals are asymptomatic. These individuals can serve as reservoirs, complicating control efforts. However, comprehensive data on asymptomatic L. donovani infections in Ethiopia are lacking, highlighting the need for a systematic review and meta-analysis to consolidate evidence and understand the distribution and determinants of this infection. Methods PRISMA guidelines followed and registered with PROSPERO (CRD42024531454). Systematically searched electronic databases and grey literature sources up to April 13, 2024. Original research articles in English considered. Statistical analyses performed using STATA version 16. Publication bias evaluated using funnel plots and Egger’s regression tests. Pooled estimate of asymptomatic L. donovani infection derived using a random effects model. Study heterogeneity assessed using Chi-square (χ²)-based Q test (p |
Document Type: |
article |
File Description: |
electronic resource |
Language: |
English |
ISSN: |
1471-2334 |
Relation: |
https://doaj.org/toc/1471-2334 |
DOI: |
10.1186/s12879-024-10275-6 |
Access URL: |
https://doaj.org/article/87b8812a05e54861b94f27b1919d382e |
Accession Number: |
edsdoj.87b8812a05e54861b94f27b1919d382e |
Database: |
Directory of Open Access Journals |
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