Prevalence of asymptomatic Leishmania donovani infection and associated factors in Ethiopia: a systematic review and meta-analysis

Bibliographic Details
Title: Prevalence of asymptomatic Leishmania donovani infection and associated factors in Ethiopia: a systematic review and meta-analysis
Authors: Habtamu Belay, Adugna Abera, Esayas Aklilu, Tesfahun Bishaw, Ayinalem Alemu, Geremew Tasew, Berhanu Erko
Source: BMC Infectious Diseases, Vol 25, Iss 1, Pp 1-13 (2025)
Publisher Information: BMC, 2025.
Publication Year: 2025
Collection: LCC:Infectious and parasitic diseases
Subject Terms: Asymptomatic, Epidemiology, Visceral leishmaniasis, L. donovani, Pooled estimate, Risk factors, Infectious and parasitic diseases, RC109-216
More Details: Abstract Background Visceral leishmaniasis is endemic in Ethiopia and caused by Leishmania donovani. Although the disease manifests with significant clinical variability, a substantial number of individuals are asymptomatic. These individuals can serve as reservoirs, complicating control efforts. However, comprehensive data on asymptomatic L. donovani infections in Ethiopia are lacking, highlighting the need for a systematic review and meta-analysis to consolidate evidence and understand the distribution and determinants of this infection. Methods PRISMA guidelines followed and registered with PROSPERO (CRD42024531454). Systematically searched electronic databases and grey literature sources up to April 13, 2024. Original research articles in English considered. Statistical analyses performed using STATA version 16. Publication bias evaluated using funnel plots and Egger’s regression tests. Pooled estimate of asymptomatic L. donovani infection derived using a random effects model. Study heterogeneity assessed using Chi-square (χ²)-based Q test (p
Document Type: article
File Description: electronic resource
Language: English
ISSN: 1471-2334
Relation: https://doaj.org/toc/1471-2334
DOI: 10.1186/s12879-024-10275-6
Access URL: https://doaj.org/article/87b8812a05e54861b94f27b1919d382e
Accession Number: edsdoj.87b8812a05e54861b94f27b1919d382e
Database: Directory of Open Access Journals
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More Details
ISSN:14712334
DOI:10.1186/s12879-024-10275-6
Published in:BMC Infectious Diseases
Language:English