Bibliographic Details
| Title: |
Analysis of risk factors and establishment of early warning model for recent postoperative complications of colorectal cancer |
| Authors: |
Yang Ou, Yang Yang, Weimin Yang, Yulin Pan, Wu Tian, Zejun Wang, Xianzhe Yu, Jihang Luo, Leibo Wang |
| Source: |
Frontiers in Oncology, Vol 14 (2024) |
| Publisher Information: |
Frontiers Media S.A., 2024. |
| Publication Year: |
2024 |
| Collection: |
LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens |
| Subject Terms: |
colorectal cancer, postoperative complications, nomogram, PNI, ASA, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282 |
| More Details: |
ObjectiveThis study aimed to analyze factors associated with recent complications after colorectal cancer surgery, constructing a nomogram to aid gastrointestinal surgeons in preoperative decision-making for patients at risk of such complications.MethodsIn this retrospective study, clinical data were collected from patients undergoing radical colorectal cancer surgery at the Department of Gastrointestinal Surgery of the Affiliated Cancer Hospital of Guizhou Medical University and the Second People’s Hospital of Chengdu from November 1, 2021, to January 26, 2024. Univariable and multivariable logistic regression analyses were conducted to assess risk factors for recent postoperative complications and develop a prediction model. External validation was performed using data from 48 postoperative colorectal cancer patients in the Second People’s Hospital of Chengdu City from January 1, 2023, to May 30, 2023. Evaluation included receiver operating characteristic (ROC) curves, calibration curves, and decision curve analysis using R4.2.2 statistical software.ResultsA total of 324 patients who underwent radical colorectal cancer surgery were enrolled. The training cohort (n=176) identified four independent risk factors for recent complications: PNI ≥45 (OR=4.17, P |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2234-943X |
| Relation: |
https://www.frontiersin.org/articles/10.3389/fonc.2024.1411817/full; https://doaj.org/toc/2234-943X |
| DOI: |
10.3389/fonc.2024.1411817 |
| Access URL: |
https://doaj.org/article/877c2aed7b7541d4a1e3e867f271e15f |
| Accession Number: |
edsdoj.877c2aed7b7541d4a1e3e867f271e15f |
| Database: |
Directory of Open Access Journals |
